Publications by authors named "B Angel"

Radioactive Ce in ionic (I-Ce), nano (N-Ce, 11 ± 9 nm mean primary particle size ± standard deviation) and micron-sized (M-Ce, 530 ± 440 µm) forms associated with natural and artificial diets in natural river water and synthetic freshwater were used to measure the real-time biokinetics of dietary Ce assimilation in a freshwater food chain. The model food chain consisted of microalgae (Raphidocelis subcapitata), snails (Potamopyrgus antipodarum) and prawns (Macrobrachium australiense). Pulse-chase experiments showed that 91-100 % of all forms of cerium associated with all diets and water types were eliminated from the digestive system of the snail and prawn within 24 h, with no detectable cerium assimilation.

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  • Ruxolitinib cream, shown to be safe and effective in a phase 3 study, has demonstrated its anti-inflammatory and itch-relieving properties in children aged 2-11 with mild to moderate atopic dermatitis (AD).
  • The study focused on assessing safety, tolerability, pharmacokinetics, and quality of life while using the cream at maximum levels over longer periods, with 29 children participating and applying the cream twice daily for 4 weeks, followed by individualized usage.
  • Results indicated that 31% of participants experienced treatment-related adverse events, but no severe health issues arose, and significant improvements in skin condition and quality of life were sustained for up to 52 weeks.
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The current work shows the advancement of an additive manufactured multiplex immunosensor for the detection of dengue serotypes 1&2 in dengue patients on a single device with the LOD of 12.5 ng/ml. In this work, we created a QR-Code enabled additive manufactured case comprised of a paper-based electrode coated with ZnO NPs, which helps to enhance the detection signal and make it more selective, both serotype antibodies (DENV1-Ab & DENV2-Ab) were employed against DENV serotypes (DENV1-Ag & DENV2-Ag.

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  • * Conducted on 58 participants aged 70 and older, the study found that frail individuals had higher rates of osteoporosis and depression and demonstrated significantly lower OCR, especially in men and those over 80.
  • * The results suggest that analyzing PBMC may provide a simple, non-invasive method for identifying early signs of frailty in aging populations.
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  • The study conducted the first genome-wide association study (GWAS) on sporadic Alzheimer's disease (AD) using a sample from Argentina and Chile, involving 539 patients and 854 controls.
  • Combining their findings with data from the European Alzheimer and Dementia Biobank (EADB), researchers identified apolipoprotein E ε4 as a significant genetic risk factor and discovered four new loci linked to AD.
  • The research highlights the shared genetic factors affecting AD risk across different populations, while also noting that a genetic risk score (GRS) showed diminishing effectiveness with increasing Native American ancestry.
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