Publications by authors named "B Allignet"
Background: Over the past two decades, the globalization of oncology clinical trials has expanded, yet significant disparities persist across countries. This study aimed to evaluate these geographical inequalities, the evolution of trial phases, and the adherence to ethical standards according to the World Bank's income group.
Materials And Methods: The ClinicalTrials.
Purpose: To compare refractive outcomes of the foldable intraocular lens sutureless scleral fixated sutureless (Carlevale® FIL-SSF) with the iris-claw lens (Artisan®).
Methods: This retrospective study included consecutive patients who underwent a FIL-SSF implantation or an iris-claw implantation between January 2020 and November 2022 in the ophthalmology departments of Hospices Civils de Lyon (France).
Results: A total of 271 eyes from 265 patients were included: 96 eyes in the FIL-SSF group and 175 eyes in the iris-claw group.
Background: Durvalumab, an anti-PD-L1 immune checkpoint inhibitor, after radio-chemotherapy (RCT) has changed the management of locally advanced non-small cell lung cancer (LA NSCLC). A series of retrospective studies have investigated different cut-off of lymphocyte count (LyC) and neutrophil-to-lymphocyte ratio (NLR) to predict survival in LA NSCLC. None of these studies has validated their threshold in an independent group of patients.
View Article and Find Full Text PDFThe carbon footprint of external beam radiotherapy and its impact in health technology assessment.
Clin Transl Radiat Oncol
September 2024
Article Synopsis
- The study evaluates the carbon footprint of external beam radiation therapy (EBRT) across four centers, identifying key factors that contribute to COeq emissions, such as treatment methods and patient transportation.
- Findings show that a typical EBRT treatment can emit between 185 kgCOeq and 2066 kgCOeq, with major contributors being accelerator maintenance, patient transportation, and medical supplies, along with notable variability between centers.
- Hypofractionation is highlighted as a significant strategy to reduce emissions, and incorporating COeq emissions into health technology assessments can positively influence the promotion of more environmentally friendly treatment regimens.
Non-seminomatous germ cell tumors (NSGCTs) represent a rare yet the most prevalent malignancy among young men. Bone metastases (BMs) are exceedingly uncommon in this neoplasm, and available data regarding the initial disease presentation, survival outcomes, and prognostic significance of BMs are limited. We conducted a retrospective analysis of 40 NSGCT patients with BMs treated between 2001 and 2021 in our tertiary care center.
View Article and Find Full Text PDF