Publications by authors named "B Alkhaffaf"

Background: The delivery of cancer services changed significantly during the COVID-19 pandemic. This study aimed to describe changes in presentations, assess the change in recommendations by the MDT during the pandemic, and describe the subsequent long-term impact of these changes on survival rates in patients with EG cancer.

Methods: A retrospective cohort study was designed comparing three patient groups of those referred to EG MDT in the same 6-month period pre-pandemic (PP;2019) during the initial phase of the pandemic (P1;2020) and the year after the initial phase (P2;2021).

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Article Synopsis
  • The study aimed to determine how many core outcome set (COS) studies include harm or adverse event outcomes, analyze the differences between individual and pooled harm outcomes, and identify factors impacting their inclusion.
  • Out of 100 reviewed COS studies from January 2021 to January 2023, 65% incorporated at least one harm outcome, with individual harms more commonly included in studies for single treatments compared to those for multiple treatments.
  • About one-third of COS developers believe harm outcomes should always be included, while over half agree it depends on the specific scope and methodology of the COS development process.
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Background: The EORTC QLQ-STO22 (QLQ-STO22) is a firmly established and validated measure of health-related quality of life (HRQoL) for people with gastric cancer (GC), developed over two decades ago. Since then there have been dramatic changes in treatment options for GC. Also, East Asian patients were not involved in the development of QLQ-STO22, where GC is most prevalent and the QLQ-STO22 is widely used.

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Background: Gastric cancer, a leading cause of cancer-related mortality worldwide, has seen limited improvement in survival over the past 3 decades. Surgical resection is the cornerstone of curative management but the optimal approach remains unclear. Decision-making is hindered by inconsistent outcome reporting limiting data synthesis between trials.

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Aim: Whilst bariatric surgery is the most effective treatment for severe obesity, the aim of this study was to evaluate whether postoperative weight loss is similar in patients with or without metabolic syndrome.

Methods: We performed a 5-year observational retrospective comparative cohort analysis of bariatric surgery in 333 patients (72% women) without (, n = 133) or with (, n = 200) metabolic syndrome at baseline.

Results: Overall mean (SD) baseline body mass index was 51.

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