Non-invasive, fast, and high-performance EGFR gene mutation prediction method based on deep transfer learning and model stacking for patients with Non-Small Cell Lung Cancer.

Purpose: To propose an intelligent, non-invasive, highly precise, and rapid method to predict the mutation status of the Epidermal Growth Factor Receptor (EGFR) to accelerate treatment with Tyrosine Kinase Inhibitor (TKI) for patients with untreated adenocarcinoma Non-Small Cell Lung Cancer.

Materials And Methods: Real-world data from 521 patients with adenocarcinoma NSCLC who performed a CT scan and underwent surgery or pathological biopsy to determine EGFR gene mutation between January 2021 and July 2022, is collected. Solutions to the problems that prevent the model from achieving very high precision, namely: human errors made during the annotation of the database and the low precision of the output decision of the model, are proposed.

Peribiliary cysts: Two case reports.

Peribiliary cysts are an incidental finding in patients with advanced liver disease. They were found to be common in fibrocystic disorders such as autosomal dominant polycystic kidney disease and polycystic liver disease, as well as cirrhotic livers. They result from obstruction-induced cystic dilatation of the peribiliary glands.

Molecular Testing for Mutation in Moroccan NSCLC Patients: CHU Hassan II-Fez Experience.

Epidermal growth factor receptor () mutation screening in non-small cell lung cancer (NSCLC) is now used to guide treatment decisions to identify patients with positive mutations that predict response to tyrosine kinase inhibitors. This study aimed to explore with a prospective study the current testing practices and the predictive value of mutations in a series of 261 patients with NSCLC. EGFR mutation testing was conducted using 2 different assays: bidirectional Sanger sequencing of polymerase chain reaction (PCR) and real-time PCR on the Rotor-Gene Q instrument.

Bilateral dolichoarteriopathy of internal carotid arteries as cause of bilateral ischemic strokes: Case report.

Most anatomic features of the internal carotid artery (ICA) are described as a straight course to the skull base free of branches. In some cases, the excessive elongation of the internal carotid artery in a confined space results in a curvature showing a "C" or "S" shape, or in an abnormal vascular shape made of a single or double vessel loop. These anatomic variants are called dolichoarteriopathies of the internal carotid artery.