A prospective study of the effect of antihypertensive medications on the sexual functions of hypertensive adult male patients.

Background: The potential for antihypertensive medications to produce deleterious adverse effects on sexual functions among hypertensive adult male patients has been widely reported, such adverse effects may limit drug adherence and compliance.

Aim: The aim of this study was to assess the effect of antihypertensive medication use on sexual functions among hypertensive adult male patients.

Methodology: The study was carried out at the outpatient clinic of a Nigerian University Teaching Hospital.

Evaluation of a recombinant DNA hepatitis B vaccine in a vaccinated Nigerian population.

Introduction: Recombinant hepatitis B vaccine was introduced in 1986 and has gradually replaced the plasma-derived hepatitis B vaccine. No published data are available on the immunogenicity of hepatitis B vaccines in Nigerians. The current study aimed to evaluate protective sero-conversion rates after vaccination with Shanvac-B rDNA hepatitis B vaccine in Nigerian subjects between January and September 2009.

Massive lower gastrointestinal haemorrhage from abdominal tuberculosis.

This is a report of a 27-year-old Nigerian male who presented with massive lower gastrointestinal haemorrhage requiring seven units of whole blood to finally stabilize him. Physical examination and other laboratory investigations as well as sigmoidoscopy were not helpful in establishing a diagnosis. Barium enema had indicated a suspicious narrowing of the transverse colon which led to advising laparotomy.