[Mechanisms of tubulo-interstitial tissue lesions of the kidneys in chronic glomerulonephritis].

The paper is concerned with a study into the mechanisms of renal interstitial lesions of the secondary character seen in patients afflicted with chronic glomerulonephritis. 120 patients with mesangioproliferative and membranous proliferative glomerulonephritis were examined. The patients were distributed into groups depending on the disease acuity, the degree of glomerular sclerosis and the disease stage.

[Structural changes in the kidney vessels in nephropathies and hypertension].

Morphological changes of the renal blood vessels were studied in 143 patients with different nephropathies and hypertensive disease. Vessels wall changes proper included: fibroelastosis, hyalinosis as well as antibodies to smooth muscle cells observed exclusively in the development of arterial hypertension. The changes were more pronounced in severe and durable hypertension.

[Mechanisms of the development of drug-induced nephropathy].

A hypothesis of the development of drug-induced nephropathy has been reviewed. The authors believe that the body sensitization to different drugs underlies drug-induced nephropathy. The sensitization may develop in the presence of congenital or acquired abnormalities leading to hemodynamic disorders in the kidneys.

[Surgical treatment of injuries and cicatricial strictures of the bile ducts using changeable transhepatic drainage].

Results of 62 reconstructive and restorative operations performed on 47 patients with scarry strictures and injuries of main bile ducts are analyzed. A group of 17 patients was chosen, a spare transhepatic drain being used in 18 operations. It was established that bougieurage, dilatation of the strictures and a continuous frame drainage with the stricture of hepaticocholedochus as long as 20 mm or recurrent strictures of hepaticojejunoanastomosis provided stabilization of scarring and epithelization of the stricture zone.