Publications by authors named "B A Yoder"
Article Synopsis
- This study investigates the effects of continuing osimertinib alongside platinum-pemetrexed chemotherapy for patients with EGFR mutant non-small cell lung cancer (NSCLC) who have had disease progression on osimertinib.
- It analyzed data from 159 eligible patients out of 421 identified, comparing outcomes between two groups: one continuing osimertinib with chemotherapy and the other receiving chemotherapy alone.
- Results showed that the group continuing osimertinib experienced a significant improvement in progression-free survival (9.0 months vs. 4.5 months), indicating a potential clinical benefit in this treatment strategy.
Article Synopsis
- * Flow cytometry analysis shows that Ift88 deficiency leads to a notable reduction in the survival of single-positive (SP) thymocytes, but only minimal effects on the overall number of T cells in the spleen and kidney.
- * The presence of Ift88 proficient T cells compensates for the loss, allowing for continued T cell population even with a deficit in Ift88 deficient cells during certain developmental stages.
Background: Bronchopulmonary dysplasia (BPD) affects up to half of extremely preterm infants, and is associated with adverse long-term respiratory, neurodevelopmental, and educational sequelae and costly health service and family economic outcomes. The NICHD Neonatal Research Network Hydrocortisone for Bronchopulmonary Dysplasia (BPD) Trial evaluated the efficacy and safety of hydrocortisone treatment to prevent BPD in high-risk infants. The trial enrolled 800 very preterm infants with respiratory failure and followed the participants until 2 years corrected age to assess safety of the trial intervention.
View Article and Find Full Text PDFObjective: We previously reported the possible pathogenic role, among infants born ≤29 weeks, of transfusions in bronchopulmonary dysplasia. The present study examined this association in infants born >31 weeks.
Study Design: Analysis of red blood cell (RBC) and platelet transfusions in five NICUs to infants born >31 weeks, and chronic neonatal lung disease (CNLD) at six-weeks of age.
Biochemistry and a large part of atmospheric chemistry occur in aqueous environments or at aqueous interfaces, where (photo)chemical reaction rates can be increased by up to several orders of magnitude. The key to understanding the chemistry and photoresponse of molecules in and "on" water lies in their valence electronic structure, with a sensitive probe being photoelectron spectroscopy. This work reports velocity-map photoelectron imaging of submicrometer-sized aqueous phenol droplets in the valence region after nonresonant (288 nm) and resonance-enhanced (274 nm) two-photon ionization with femtosecond ultraviolet light, complementing previous liquid microjet studies.
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