Publications by authors named "B A Vogt"
Introduction: Multicenter research initiatives in Brazilian dialysis centers are scarce. We described the recruitment and implementation phases of the SARC-HD study, aimed at investigating sarcopenia and its impact on adverse clinical outcomes.
Methods: The SARC-HD is a cohort study being conducted with patients on hemodialysis in Brazil.
Objective: Adrenomedullin (ADM) is a potent vasodilator. The association between plasma ADM levels and blood pressure (BP) remains unclear. We assessed the association between mid-regional-pro-ADM (MR-proADM) and BP in a multicenter population- and family-based cohort.
View Article and Find Full Text PDFArticle Synopsis
- IgA vasculitis (IgAV) is a pediatric disease characterized by skin and systemic symptoms, and researchers conducted comprehensive studies involving genome, transcriptome, and proteome analyses on a large cohort of IgAV patients and controls to better understand the disease mechanisms.* -
- Significant associations were found with specific genetic risk factors, including two novel non-HLA loci linked to IgA receptor functioning, which may contribute to disease development through altered immune responses.* -
- Systems biology approaches helped identify key regulatory networks and master regulators in myeloid cells, along with 21 genetic loci that overlap with IgA nephropathy, suggesting shared pathways in these related conditions.*
Article Synopsis
- Low muscle strength and function are linked to negative health outcomes in hemodialysis patients, yet reference values for muscle and physical performance tests are scarce.
- A large-scale analysis was conducted using baseline data from the SARC-HD study, focusing on handgrip strength, sit-to-stand tests, and gait speed, with results segmented by sex and age.
- Findings indicated that muscle strength and physical performance declined with age, with notable differences between males and females, and highlighted specific reference values that could serve as clinical markers for identifying patients at risk.