Publications by authors named "B A Schoonderwoerd"
Aims: Recently, a genetic variant-specific prediction model for phospholamban (PLN) p.(Arg14del)-positive individuals was developed to predict individual major ventricular arrhythmia (VA) risk to support decision-making for primary prevention implantable cardioverter defibrillator (ICD) implantation. This model predicts major VA risk from baseline data, but iterative evaluation of major VA risk may be warranted considering that the risk factors for major VA are progressive.
View Article and Find Full Text PDFBackground: Phospholamban (PLN) p.(Arg14del) variant carriers are at risk for development of malignant ventricular arrhythmia (MVA). Accurate risk stratification allows timely implantation of intracardiac defibrillators and is currently performed with a multimodality prediction model.
View Article and Find Full Text PDFAims: This study aims to improve risk stratification for primary prevention implantable cardioverter defibrillator (ICD) implantation by developing a new mutation-specific prediction model for malignant ventricular arrhythmia (VA) in phospholamban (PLN) p.Arg14del mutation carriers. The proposed model is compared to an existing PLN risk model.
View Article and Find Full Text PDFAims: Laserballoon-based pulmonary vein isolation (PVI) for the treatment of atrial fibrillation (AF) has proven safe and effective. Silent brain lesions after AF ablation detected on magnetic resonance imaging (MRI) have been described for several technologies, but its incidence following laserballoon PVI is unknown. The current study sought to assess the incidence of new asymptomatic brain lesions in patients undergoing laserballoon-based PVI.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the long-term outcomes of catheter ablation for left posterior fascicular ventricular tachycardia (LPF VT) performed during sinus rhythm rather than during an active tachycardia episode.
- A group of 24 patients was analyzed, and the ablation targeted the earliest signs of retrograde activation within the posterior Purkinje fiber network; 87.5% of patients had successful outcomes without any procedure-related complications.
- After nearly 9 years of follow-up, 92% of the patients remained free from recurrent VT, indicating that this approach yields excellent long-term results.