[The use of a soy protein isolate in the diet therapy of patients with alimentary obesity].

Patients with alimentary obesity received a diet with 1/3 amount of protein substituted for soya protein isolate, daily, during 4 weeks. The influence of the dietotherapeutic course on protein, lipid metabolism, on bile acid and lipid composition of bile and on the immunologic state of the patients was studied. Blood and bile lipid content and the fraction of cholesterol esters were studied by thin-layer chromatography, lipid composition by disc electrophoresis in polyacrylamide gel, protein fractions by paper electrophoresis; the immunologic state was studied by the blast-transformation test and immunoglobulin assay.

[The prevalence of obesity among the adult population of Kazakhstan].

The questionnaire method was used to study obesity incidence among 25107 subjects over 15 years of age living in the Northern, Southern and Western regions of Kazakhstan. Anthropometry was conducted, and incidence rate of certain diseases in the investigated subjects was recorded. Excessive body mass was revealed in 36.

[The role of nutritional factors in the development of obesity among the adult residents of Kazakhstan].

Etiologic factors of obesity were studied by the questionnaire method in the population of Kazakhstan aged over 15 years. Among 4912 subjects with excessive body mass alimentary disorders promoting the development of obesity were detected in 32.6%, low energy expenditure--in 26.

[Role of modern diet therapy in the prevention of visceral complications in patients with dietary obesity].

The examination and treatment of 547 patients with alimentary obesity revealed in them significant impairments of myocardial contractility, manifest hemodynamic disorders (in 65.5% of patients), marked changes in lipid metabolism (hypercholesterolemia, hypertriglyceridemia, hyperlipacidemia, hyperlipoproteinemia type IIa in 26,5%, type IIb in 14,5%, type IV in 32,5% of patients), as well as reduced activity of the T-immunity system, all these changes being prerequisites for the development of atherosclerosis, ischemic heart disease and essential hypertension. During examination of the patients' liver, fatty hepatosis was detected in 91.

[Effects of diet therapy on protein, lipid and carbohydrate metabolism in patients with alimentary obesity].

Lipid, protein and carbohydrate metabolism was studied in patients with alimentary obesity as was the effect on that metabolism of the diets containing horseflesh and beef. The majority of the obese patients showed an increased content of all lipid fractions (phospholipids, cholesterol, free fatty acids, triglycerides), of very low and low density lipids, and a reduced content of high density lipoproteins. Normolipoproteinemia was only ascertained in 26.