Regulation of RASSF by non-coding RNAs in different cancers: RASSFs as masterminds of their own destiny as tumor suppressors and oncogenes.

Ras-association domain family (RASSF) proteins are tumor suppressors and have gained phenomenal limelight because of their mechanistic role in the prevention/inhibition of carcinogenesis and metastasis. Decades of research have demystified wide ranging activities of RASSF molecules in multiple stages of cancers. Although major fraction of RASSF molecules has tumor suppressive roles, yet there is parallel existence of proof-of-concept about moonlighting activities of RASSF proteins as oncogenes.

Tympanoplasty and adenoidectomy in children: Comparison of simultaneous and sequential approaches.

Background: The authors sought to compare simultaneous and sequential tympanoplasty and adenoidectomy surgery in pediatric patients.

Methods: This retrospective single-center study included 65 children (36 males, 29 females; mean age 9.16 ± 3.

[MODIFICATION OF CARDIOVASCULAR RISK WITH A COMBINATION OF METABOLIC SYNDROME AND VEGETATIVE NERVOUS DYSFUNCTION].

The aim of the study was to identify the effect of vegetative nervous dysfunction on the level of cardiovascular risk in persons with metabolic syndrome undergoing intensive monitoring. The survey involved 750 civil servants aged 35 to 70 years, including 476 men and 274 women. Diagnosis of the metabolic syndrome (MS) was carried out according to the IDF and AHA / NHLBI consensus criteria (2009).

[Activity of digestive enzymes in offspring of rats fed a ration contaminated by heavy metals during lactation].

Is was shown the consumption of heavy metal's salts with food by lactating rats, essential influences on formation of mechanisms of cavity and membrane digestive in offspring. This influence is shown in repression of activity of pancreatic alpha-amylase and enteral saccrase, maltase as well as in induction of lactase activity in growing rats.