[Immunocorrective therapy of the traumatic syndrome].

The effect of combined application of thymalin and plaferon in the prophylaxis and treatment of traumatic syndrome has been investigated in rats. The survival rate was taken as the criterion of efficiency, the mechanism of the effect obtained being estimated at the level of immunological protective factors. Traumatic shock was induced by Kennon's method in Wistar male rats weighing 200-250 g.

[Dynamics of changes in pulmonary catecholamine content and lipid fatty acid composition in traumatic shock].

The content of noradrenaline in the lungs, pulmonary arteries and veins was found to be reduced at definite stages of traumatic shock. At the same time the level of oleic acids was decreased in pulmonary lipid fractions. The content of adrenaline rose in the pulmonary arteries and veins, and it was high in the blood collected from the right atrium as compared to the blood from the carotid artery.

[Ultrastructural changes in the hepatic mast and plasma cells of pregnant rats with endotoxic shock].

Ultrastructural alterations in mast and plasma cells of pregnant rat liver were studied in the initial period of endotoxin shock. A significant increase in functional activity of mast and plasma cells and the presence of intercellular contacts and contacts with cells of perisinusoidal space were found. The data obtained suggest that endotoxin stimulates connective tissue cells, leading to the release of mediators and biologically active substances responsible for hepatic injury during endotoxemia.