Adverse Effects of Chemotherapy and the Interaction With Anesthesia: A Narrative Review.

Many cancer patients have their main tumors surgically removed with the goal of curing them, or as part of palliative care. When a patient receives general anesthesia, the side effects of the administered chemotherapy regimens must be considered, especially those that may have significant repercussions during anesthetic care. The aim of this study is to review the existing literature to identify adverse effects of chemotherapy and known interactions between chemotherapy and anesthetic drugs, analyze the mechanisms underlying these interactions, and discuss relevant clinical implications.

Should patients with encrusted JJ stents involving the proximal/renal loop undergo primarily endoscopic combined intrarenal surgery?

Background: Ureteral stents are one of the most used devices in Urology, allowing drainage of the upper urinary system, and can be used either in elective or emergency procedures. However, as a foreign body inside the urinary system, they are subject to encrustation. Encrustation is one of the burdens seen with double-J stents and, to date, there is no consensus about its best management.

Responders COPD patients to two different home-based rehabilitation programs: a blind, randomized, and controlled clinical trial.

Purpose: To verify the number of patients with COPD responders to two different home-based rehabilitation programs.

Methods: This was a blinded, randomized, and controlled clinical trial. The six-minute step test (6MST), one-minute sit-stand test (1-MSTST), six-minute walk test (6MWT), COPD Assessment Test (CAT), modified Medical Research Council (mMRC), monitoring of physical activity in daily life, and isometric quadriceps muscle strength were assessed pre- and post-intervention.

Caffeine intake during gestation and lactation causes long-term behavioral impairments in heterogenic mice offspring in a sex-dependent manner.

Growing evidence has indicated a potential association between maternal consumption of caffeine and impaired cognition and behavior in rodent offspring. However, potential sex differences, as well as caffeine-related effects in subsequent generations are still poorly investigated. We aimed to investigate the impact of pre-and/or neonatal exposition to caffeine on the neurodevelopment of male and female mice offspring.

Annual 30-m maps of global grassland class and extent (2000-2022) based on spatiotemporal Machine Learning.

The paper describes the production and evaluation of global grassland extent mapped annually for 2000-2022 at 30 m spatial resolution. The dataset showing the spatiotemporal distribution of cultivated and natural/semi-natural grassland classes was produced by using GLAD Landsat ARD-2 image archive, accompanied by climatic, landform and proximity covariates, spatiotemporal machine learning (per-class Random Forest) and over 2.3 M reference samples (visually interpreted in Very High Resolution imagery).