HPV Vaccination and Awareness Programs at Maryland Colleges and Universities.

Context: About half of adolescents aged 13 to 17 in United States are not fully vaccinated against human papillomavirus (HPV). As they age into young adulthood, colleges may be an excellent target population nexus for implementing interventions to improve HPV vaccination uptake.

Objectives: Our study goal was to generate knowledge about HPV vaccine offerings and awareness programs at colleges to ascertain the extent of campus-facilitated access to HPV immunization and education in 1 state.

Cigarette Smoking, Mental Health, Depression, Maryland Behavioral Risk Factor Surveillance System Survey, 2020.

Background: Smoking cessation is linked to improved mental health that encompasses the overall well-being and psychological functioning of an individual.

Objective: Examine relationships between smoking, mental health, and social connectedness among adults in Maryland, US in 2020.

Methodology: This cross-sectional study used data from the Maryland 2020 Behavioral Risk Factor Surveillance System Survey of adults during the onset of COVID-19.

Conditional loss of CaMKK2 in Osterix-positive osteoprogenitors enhances osteoblast function in a sex-divergent manner.

Ca/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a multi-functional, serine/threonine protein kinase with predominant roles in inflammation, systemic energy metabolism, and bone remodeling. We previously reported that global ablation of CaMKK2 or its systemic pharmacological inhibition led to bone mass accrual in mice by stimulating osteoblasts and inhibiting osteoclasts. However, a direct, cell-intrinsic role for the kinase in the osteoblast lineage has not been established.

Self-expansion within sexual minority relationships.

According to the self-expansion model, people increase their positive self-concept content when they form and maintain romantic relationships, and self-expansion is an important predictor of relationship outcomes. Although thought to be universal, no prior research has examined self-expansion among sexual minority individuals. In the current study, sexual minority ( = 226) and heterosexual ( = 104) participants completed measures of self-expansion and relationship outcomes, and sexual minority participants completed measures of sexual minority stress.

Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin.

Calcium/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) regulates bone remodeling through its effects on osteoblasts and osteoclasts. However, its role in osteocytes, the most abundant bone cell type and the master regulator of bone remodeling, remains unknown. Here we report that the conditional deletion of CaMKK2 from osteocytes using Dentine matrix protein 1 ()-8kb- mice led to enhanced bone mass only in female mice owing to a suppression of osteoclasts.