Publications by authors named "B A Leggett"

Article Synopsis
  • - This study investigates Mycoplasma bovis (M. bovis) infection in cattle, which can cause various health issues, aiming to analyze the genetic diversity of M. bovis strains from clinical samples in Ireland and Scotland.
  • - Researchers sequenced the genomes of 24 M. bovis strains (19 from Ireland and 5 from Scotland) and compared them to 117 existing genetic assemblies to create a phylogenetic tree, identifying Irish strains in two groups and all Scottish strains in one.
  • - The findings highlight the similarities between Irish and Scottish M. bovis strains and underscore the importance of biosecurity in cattle management due to the global spread of this infection facilitated by international cattle movement.
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Background: Little is known regarding long-term consequences (≥5 years) of sport-related concussion (SRC) sustained during adolescence. Adolescent SRC has been linked to athlete considerations of sport participation and subsequent retirement from sport during this critical developmental period. Prolonged SRC symptoms can reduce ability to perform physical activity, and research suggests inactivity can extend years post-injury.

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Introduction: Alcohol use is common in patients with chronic hepatitis C virus (HCV) infection. We examined the impact of alcohol use on direct-acting antiviral (DAA) therapy outcome and the clinical course of liver disease and 2-year survival for patients receiving HCV DAA therapy.

Methods: Adults (n = 2624) recruited from 26 Australian hospital liver clinics during 2016-2021 were followed up for 2 years.

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Background And Aim: Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with an increased risk of extrahepatic morbidity. We compared the incidence of cancers in adults admitted to Queensland hospitals with MASLD with that for the Queensland population and examined the association between cirrhosis and type 2 diabetes and the development of extrahepatic cancers.

Methods: In this retrospective study, we identified all cancers (Queensland Cancer Registry) after the first hospitalization with MASLD during Jul-2007 to Dec-2019, estimated age-standardized incidence (ASI) of cancers, and compared that with the ASI in the Queensland population (incidence rate ratios [IRR]).

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We present a case of Cronkhite-Canada syndrome in a patient with decompensated cirrhosis who had successful induction of remission with nutritional supplementation alone. We propose that early institution of high-protein, high-energy enteral supplementation should be offered to all patients, especially those with compelling contraindications to immunosuppression.

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