Publications by authors named "B A Kovarsky"
Article Synopsis
- * A study showed that HP eradication therapy significantly reduced gut microbiota diversity and altered the abundance of various microbial species.
- * Changes in antibiotic resistance genes (ARGs) were observed post-therapy, with some strains exhibiting higher resistance to specific antibiotics like macrolides and tetracyclines compared to others.
Article Synopsis
- Crohn's disease is linked to imbalances in gut bacteria, specifically with an increase in certain types of E. coli, and more research is needed to understand their role.
- A metagenomic study of Crohn's patients showed that the gut microbiomes varied significantly between individuals, revealing high genetic diversity in E. coli strains.
- The findings suggest that understanding the genetic diversity of these bacteria can help develop better prevention and treatment options for Crohn's disease.
The abundance of Enterococci in the human intestinal microbiota environment is usually < 0.1% of the total bacterial fraction. The multiple resistance to antibiotics of the opportunistic spp.
View Article and Find Full Text PDFBackground: Alcohol abuse has deleterious effects on human health by disrupting the functions of many organs and systems. Gut microbiota has been implicated in the pathogenesis of alcohol-related liver diseases, with its composition manifesting expressed dysbiosis in patients suffering from alcoholic dependence. Due to its inherent plasticity, gut microbiota is an important target for prevention and treatment of these diseases.
View Article and Find Full Text PDFGut microbiota of patients with Parkinson's disease and healthy volunteers was analyzed by the method of high throughput 16S rRNA sequencing of bacterial genomes. In patients with Parkinson's diseases, changes in the content of 9 genera and 15 species of microorganisms were revealed: reduced content of Dorea, Bacteroides, Prevotella, Faecalibacterium, Bacteroides massiliensis, Stoquefichus massiliensis, Bacteroides coprocola, Blautia glucerasea, Dorea longicatena, Bacteroides dorei, Bacteroides plebeus, Prevotella copri, Coprococcus eutactus, and Ruminococcus callidus, and increased content of Christensenella, Catabacter, Lactobacillus, Oscillospira, Bifidobacterium, Christensenella minuta, Catabacter hongkongensis, Lactobacillus mucosae, Ruminococcus bromii, and Papillibacter cinnamivorans. This microbiological pattern of gut microflora can trigger local inflammation followed by aggregation of α-synuclein and generation of Lewy bodies.
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