Publications by authors named "B A Kapetanakis"
Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial.
Denis Azzopardi Nicola J Robertson Alan Bainbridge Ernest Cady Geoffrey Charles-Edwards Basil Kapetanakis
Lancet Neurol
February 2016
Article Synopsis
- Moderate cooling post-birth asphyxia has been shown to reduce death and disability, and researchers explored the potential added benefits of xenon gas in combination with this treatment.
- A trial involving 92 infants was conducted to assess the effectiveness of total body hypothermia plus xenon against standard cooling treatment, with specific neurological outcomes measured within 15 days after birth.
- The trial, completed in 2014, randomly assigned infants to either standard cooling or cooling with xenon, aiming to determine if the latter could improve brain health outcomes after asphyxia.
Objective: The aim of this study was to examine the relationship between cortical development and cerebral electrical activity at early gestational ages.
Methods: We obtained EEGs (7.2+/-3.