Publications by authors named "B A Hidalgo"
Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in human blood. The presence of mLOY is associated with altered blood cell counts and increased risk of Alzheimer disease, solid tumors, and other age-related diseases. We sought to gain a better understanding of genetic drivers and associated phenotypes of mLOY through analyses of whole-genome sequencing (WGS) of a large set of genetically diverse males from the Trans-Omics for Precision Medicine (TOPMed) program.
View Article and Find Full Text PDFThe effects of foot core exercises and minimalist footwear on foot muscle sizes, foot strength, and biomechanics: A systematic review and meta-analysis.
Clin Biomech (Bristol)
December 2024
Background: Specific foot exercises and the use of minimalist shoes during running or daily life were suggested to strengthen the intrinsic foot muscles and to modify locomotion biomechanics. We aimed to review the effectiveness of these interventions to modify foot muscle sizes, foot strength, and biomechanical outcomes.
Method: PubMed, Embase, Cochrane Library and SportDiscus databases were searched (last update: 12 March 2024).
Article Synopsis
- * This study is the first large-scale analysis examining the relationship between EDS and genetic variations related to OSA severity, using data from over 11,500 samples across diverse populations.
- * Researchers identified 16 genetic targets linked to EDS and OSA, with eight being new discoveries, and discussed potential therapeutic implications involving insulin resistance and nutritional factors for patients with OSA and EDS.
Background: Research examining the relationship between psychological factors and COVID-19 vaccine hesitancy has been mostly based on observational designs, with little attention devoted to the role of exposure to objective/sensationalist information.
Purpose: This experimental study examined the extent to which exposure to objective or sensationalist news headlines: 1) influenced COVID-19 anti-vaccination attitudes; and 2) moderated the relationship between psychological factors and COVID-19 anti-vaccination attitudes.
Methods: 123 participants (mean age = 28.
Article Synopsis
- Chronic kidney disease (CKD) affects about 1 in 7 adults in the U.S., especially African Americans who are more likely to suffer from it.
- Scientists discovered that certain changes in DNA can help predict who might get CKD, focusing on specific sites in the DNA.
- The study created a special score using these DNA changes to see how likely someone is to have CKD and found it works well for African Americans, suggesting it could help in checking kidney health in the future.