Publications by authors named "B A Dave"
Introduction: Conservative and surgical approach timeline in post-operative spondylodiscitis (POS) following lumbar disc herniation (LDH) surgery is ill defined, and patients have a protracted recovery phase with social, psychological, and financial implications.
Material And Methods: Retrospective analysis of patients operated by transforaminal lumbar interbody fusion (TLIF) in POS was done. Confirmed clinico-radiological diagnosed POS cases, not responding within three to four weeks were included.
Article Synopsis
- * Human-derived brain tumor cell lines also face challenges, making them inadequate for certain pre-clinical modeling tasks.
- * The article advocates for utilizing human stem cell-based models, such as two-dimensional cultures and three-dimensional organoids, as promising alternatives to traditional models for better understanding and treating brain tumors like glioblastoma and medulloblastoma.
Article Synopsis
- High-grade B-cell lymphoma not otherwise specified (HGBCL, NOS) shares similarities with diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL), which complicates its diagnosis and treatment.
- A study on a cohort of 55 patients revealed that about 60% of HGBCL, NOS cases don't express the BL gene signature and instead display characteristics aligned with DLBCL, while showing significant genetic diversity and changes in critical regulatory genes.
- Pediatric HGBCL, NOS cases exhibited gene expressions typical of GCB-DLBCL and also showed key mutations seen in pediatric BL; the research highlighted PIM1 mutations in adults as a potential target for new therapies.
Managing Ocular Surface Disease in Glaucoma Treatment: A Systematic Review.
Bioengineering (Basel)
October 2024
Ocular surface disease (OSD) is a frequent disabling challenge among patients with glaucoma who use benzalkonium chloride (BAK)-containing topical glaucoma medications for prolonged periods. In this comprehensive review, we evaluated the prevalence of OSD and its management, focusing on both current and future alternatives. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were used to assess a) the impact of active ingredients and preservatives on the ocular surface and b) the efficacy of preservative-free (PF) alternatives and adjunctive therapies.
View Article and Find Full Text PDFStudy Design: Retrospective observational study.
Purpose: This study aimed to evaluate the utility of cervical dynamic magnetic resonance imaging (dMRI) in the assessment of cervical canal stenosis.
Overview Of Literature: Cervical spondylotic myelopathy has been intricately linked to both static and dynamic narrowing of the cervical spinal canal.