[Effect of insulin on lipid peroxidation in the erythrocyte membranes of patients with insulin dependent diabetes mellitus].

The spin-probe techniques has been used to study insulin-membranes interaction in erythrocytes by insulin dependent diabetes mellitus. The lipid peroxidation has been initiated by FeSO4-ascorbate. It was found the insulin defend the lipids in control by peroxidation, but no effect in insulin dependent diabetes mellitus erythrocytes.

[The structural status of red blood cell membranes in children with insulin-dependent diabetes mellitus. Examination by spin probe].

Using spin probes-stearic acid analogues, the authors investigated the microviscosity and the a/b parameter of red blood cell membranes in children with diabetes mellitus. The structural changes were correlated with altered metabolic measurements. The change in the pathway of insulin in diabetes mellitus led to the structural state of red blood cell membranes.

[ESR-spectroscopy in medical practice and biomedical research].

The authors describe the use of the ESR technique during the past 20 years. There are many examples of the application of the technique in different investigations. The authors propose the new way of training medical students to apply it.

[Recording of surface potential changes in erythrocyte membranes from patients with insulin-dependent diabetes mellitus using a spin probe method].

Changes in surface potential of erythrocyte membranes were studied by a positively charged analog as a spin probe. Insulin-dependent diabetes mellitus (IDDM) patients demonstrated a significant increase (by 16 +/- 2.0 mV) in negative surface potential as compared to the control.