Publications by authors named "B A B Essers"
Background: Discrete choice experiments (DCEs) are increasingly used to understand and quantify patient preferences for a variety of treatments, services or screening in order to analyse the choices patients make when faced with different alternatives. The aim of this DCE was to examine patient preferences for the treatment of Bowen's disease.
Methods: A DCE was conducted alongside a randomised controlled non-inferiority trial comparing the effectiveness of surgical excision, MAL-PDT, and 5-fluorouracil cream as treatments for Bowen's disease.
Article Synopsis
- - The study investigates patient preferences regarding new genetic therapies for polyglutamine expansion diseases like Huntington's disease and spinocerebellar ataxia, focusing on factors such as treatment administration and expected benefits.
- - Researchers collected data from 216 patients through an online questionnaire that presented them with various treatment options, assessing their preferences based on multiple attributes using a discrete choice experiment.
- - Findings reveal that patients favor less invasive treatment methods, such as a single operation over repeated lumbar punctures, and they are more inclined towards interventions with higher chances of benefit, while risk and follow-up aspects seem less influential in their decision-making.
Background: Several initiatives have been developed to target low-value care (ie, waste) in decision-making with varying success. As such, decision-making is a complex process and context's influence on decisions concerning low-value care is limitedly explored. Hence, a more detailed understanding of residents' decision-making is needed to reduce future low-value care.
View Article and Find Full Text PDFContrast-enhanced mammography versus conventional imaging in women recalled from breast cancer screening (RACER trial): a multicentre, open-label, randomised controlled clinical trial.
Lancet Reg Health Eur
September 2024
Background: Women recalled from breast cancer screening receive post-screening work-up in the hospital with conventional breast imaging. The RACER trial aimed to study whether contrast-enhanced mammography (CEM) as primary imaging instead of conventional imaging resulted in more accurate and efficient diagnostic work-up in recalled women.
Methods: In this randomised, controlled trial (registered under NL6413/NTR6589) participants were allocated using deterministic minimisation to CEM or conventional imaging as a primary work-up tool in two general and two academic hospitals.
Background: For various genetic disorders characterized by expanded cytosine-adenine-guanine (CAG) repeats, such as spinocerebellar ataxia (SCA) subtypes and Huntington's disease (HD), genetic interventions are currently being tested in different clinical trial phases. The patient's perspective on such interventions should be included in the further development and implementation of these new treatments.
Objective: To obtain insight into the thoughts and perspectives of individuals with SCA and HD on genetic interventions.