Publications by authors named "B A Anantharam"
Background: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has evolved a great deal over recent years, with increased procedural success and lower complication rates being reported. This study aims to evaluate the feasibility, safety and success of a dedicated CTO programme in a large UK PCI centre without on-site cardiothoracic surgery facilities.
Methods: Clinical and procedural data were retrospectively collected for consecutive unselected patients undergoing CTO PCI between 2015 and 2019 from the local database and regional electronic patient records.
Article Synopsis
- Cardiac surgery for coronary artery disease decreased significantly during the first COVID-19 pandemic wave, leading many patients to receive percutaneous coronary intervention (PCI) instead of the usual coronary artery bypass grafting (CABG).
- A study tracked 215 patients who underwent PCI, gathering 12-month outcomes like death, heart attacks, and other complications to evaluate the procedure's effectiveness.
- Results showed that after a year, PCI had acceptable outcomes with low rates of major adverse events, suggesting the need for further research comparing PCI to CABG in similar patient populations.
Article Synopsis
- The study aimed to assess if a very early invasive strategy (IS) with possible revascularisation improves outcomes compared to standard care for high-risk patients with non-ST-elevation acute coronary syndrome (NSTE-ACS).
- 425 patients were randomly assigned to either very early IS (within 90 minutes) or standard IS (within 72 hours), but the trial was halted early due to slow recruitment amid the COVID-19 pandemic.
- At 12 months, there were no significant differences in clinical outcomes between the two groups, although the very early IS group had a shorter hospital stay.
Background: Duchenne's muscular dystrophy (DMD) is an X-linked muscular disease which is caused by the absence of dystrophin. This results in the death of muscle cells and cardiomyocytes and consequent substitution by fat and fibrous tissue. The clinical translation of this is muscle weakness and cardiomyopathy.
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