Exploring Alternative Treatment Choices for Multidrug-Resistant Clinical Strains of in Mongolia.

is a pathogen related to severe diseases such as gastric cancer; because of rising antimicrobial-resistant strains, failure to eradicate with antibiotics has increased worldwide. Multidrug-resistant and gastric cancer is common in Mongolia; therefore, we aimed to explore alternative antimicrobial treatments and the genomes of resistant strains in this country. A total of 361 strains isolated from patients in Mongolia were considered.

Study of Isolated from a High-Gastric-Cancer-Risk Population: Unveiling the Comprehensive Analysis of Virulence-Associated Genes including Secretion Systems, and Genome-Wide Association Study.

Background: The prevalence of gastric cancer in Mongolia, in East Asia, remains the highest in the world. However, most strains in Mongolia have a less virulent Western-type CagA. We aimed to determine how genomic variation affected gastric diseases, especially gastric cancer, based on comprehensive genome analysis.

Utilization of an Automated Latex Agglutination Turbidity Assay for Assessing Gastric Mucosal Alteration during Infection.

Background/aims: : A latex agglutination turbidity (LA) assay to test for serum antibodies has been approved in Japan and Korea for mass screening of infection. In this study, we evaluated the LA assay for diagnosing infection and predicting gastric mucosal changes in a Mongolian population.

Methods: : In total, 484 individuals were classified into -positive (n=356) and -negative (n=128) groups, as determined by histology and culture.

Pepsinogen and Serum IgG Detection Is a Valuable Diagnostic Method for Infection in a Low-Prevalence Country: A Report from Sri Lanka.

The use of serum anti- IgG and pepsinogen (PG) detection as a diagnostic method was evaluated in Sri Lanka. Gastric biopsies were performed (353 patients), and the prevalence of infection was 1.7% (culture) and 2.

Advantage of 16S rRNA amplicon sequencing in Helicobacter pylori diagnosis.

Background: 16S rRNA amplicon sequencing is an accurate method of detecting microbial infection without culture. It is unclear if sequencing has additional benefits over routine diagnostic methods for Helicobacter pylori testing.

Methods: We enrolled Mongolian volunteers with dyspepsia.

High Antibiotic Resistance of and Its Associated Novel Gene Mutations among the Mongolian Population.

Mongolia has a high prevalence of infection and the second highest incidence of gastric cancer worldwide. Thus, investigating the prevalence of antibiotic resistance and its underlying genetic mechanism is necessary. We isolated 361 strains throughout Mongolia.

Western-Type CagA are the Most Frequent Type in Mongolian Patients.

infection possessing East-Asian-type CagA is associated with carcinogenesis. Mongolia has the highest mortality rate from gastric cancer. Therefore, we evaluated the CagA status in the Mongolian population.

Gastric Microbiota in -Negative and -Positive Gastritis Among High Incidence of Gastric Cancer Area.

() related chronic gastritis is a well-known major etiological factor for gastric cancer development. However, -negative gastritis (HpN) is not well described. We aimed to examine gastric mucosal microbiota in HpN compared to -positive gastritis (HpP) and -negative non-gastritis group (control).

New observations regarding Helicobacter pylori and gastric cancer in Mongolia.

Background: The incidence and mortality of gastric cancer in Mongolia is among the highest in the world.

Methods: This was a case-control study in which upper gastrointestinal endoscopy, gastric histology, Helicobacter pylori testing, and risk factor questionnaires were obtained. Histologic subtypes were determined by Lauren's classification.

The prevalence of infection and other risk factors among Mongolian dyspeptic patients who have a high incidence and mortality rate of gastric cancer.

Background: Mongolia has not only the second highest incidence rate but also the highest mortality rate for gastric cancer globally. In addition to gastric cancer, ulcerative disease complications are also life threatening; thus, investigating infection and other risk factors is essential.

Results: infection was high in tested dyspeptic patients from all parts of Mongolia, with an overall infection rate of 80.