Efficacy of rituximab in refractory polyarteritis nodosa: a case report.

Polyarteritis nodosa (PAN) is a systemic vasculitis affecting medium and small-sized vessels resulting in multiple organ involvement. Refractory PAN requires a different therapeutic approach. We herein report the case of a 42-year-old male presenting a non-virus-related refractory PAN with a favorable outcome on rituximab.

Family medicine: attractiveness, constraints and prospects as perceived by residents of the specialty.

Introduction: Medical studies reform in Tunisia was conducted to upgrade general medicine, depreciated by the population and experienced by practitioners as a path of failure, thus elevated to the rank of family medicine (FM).

Aim: To determine the factors of attractiveness of the FM, the prospects and career aspirations of future family physicians.

Methods: We conducted a cross-sectional survey by an anonymous questionnaire distributed via an online questionnaire platform from February 11th to April 13th, 2018 that targeted students in the 2nd year of FM at the Faculty of Medicine of Tunis.

Gelatinous Transformation of Bone Marrow in a Patient with Anorexia Nervosa: An Uncommon but Reversible Etiology.

BACKGROUND Anorexia nervosa is a relatively frequently encountered eating disorder. Beyond its psychiatric significance, it is associated with multiple hematological features such as cytopenia. It can be related to gelatinous transformation of the bone marrow.

[Hypercalcemia related to PTH-rP revealing malignant hepatic epithelioid hemangioendothelioma].

Hypercalcemia caused by tumor production of PTH-rp occurs most often in cases of squamous cell carcinoma of the lung, aerodigestive tract cancer, gynecological cancer and lymphoma. We report an exceptional case of PTH-rp related to a hepatic hemangioendothelioma. A 70 years-old male admitted for deterioration of the general state.

[Characteristics of deep vein thrombosis in the elderly].

Purpose Of The Study: Deep vein thrombosis is a common condition in geriatric. The identification of risk factors for venous thrombosis in the elderly is important because it allows an appropriate prescription of preventive treatments. The purpose of this study is to identify the etiologic and therapeutic characteristics of deep vein thrombosis of the lower limbs in the elderly.

[Syndrome d'activation macrophagique: une série de 11 cas tunisiens].

Background: Hemophagocytic syndromes are mostly associated with underlying pathology, they can reveal: immunodeficiency, infections, hemopathies, cancers and auto-immune diseases.

Aim: to investigate clinical, biological features, outcome characteristics and underlying pathology of Tunisian patients with hemophagocytic syndromes.

Methods: A retrospective study of patients with hemophagocytic syndromes admitted in an internal medicine department in Tunis over the period 2009-2012.

Orbital metastasis as the inaugural presentation of occult rectal cancer.

Orbital metastasis is uncommon and occurs in 2-3% of patients with cancer. It is rarely the initial manifestation of a systemic malignancy. It usually indicates extensive haematogenous dissemination of a primary cancer and is associated with poor prognosis.

Isolated caecal tuberculosis mimicking a neoplastic tumour in an immunocompetent woman.

Although tuberculosis is endemic in Tunisia, only a few cases of intestinal disease have been reported. This entity is usually associated with pulmonary tuberculosis. Any part of the gastrointestinal tract may be affected but usually with ileocaecal involvement.

[A leukemoid leucocytosis].

Leukemoid reaction is a rare paraneoplastic syndrome. It can occur in association with carcinomas, in particular of the lung, gastric and renal. However, its association with sarcoma is infrequent.

[Renal amyloidosis during Behçet's disease. Study of one case].

Background: Amyloidosis in Behçet's disease is rare and has a poor outcome.

Aim: Report a new case.

Case: We report a case of a 38-year-old Tunisian woman who presented with Behçet's disease and nephrotic syndrome.

[Chronic disseminated intravascular coagulation caused by aortic dissection].

Background: Disseminated intravascular coagulation (DIC) is a severe disease. It can be caused by loss of pathology.

Case Report: We report the case of chronic aortic dissection discovered during the evaluation of disseminated intravascular coagulation (DIC).