Background: The search for an ideal anchorage during orthodontic treatment resulted in the invention of Orthodontic Mini Implants (OMIs) that do not require patient's cooperation. In spite of their common use in orthodontics, there is a lack of studies regarding patients' perceptions of OMIs after their immediate and delayed loading.
Aim: The aim of this study was to compare the pain and discomfort experienced by patients following the placement of orthodontic mini-implants and immediate loading with delayed loading, and to evaluate their success rate to formulate a definite clinical protocol for loading of the orthodontic mini-implants.