Publications by authors named "Azusa Orihara"

Article Synopsis
  • - A 75-year-old man experienced a headache and altered consciousness, leading to an MRI that showed brain edema and contrast enhancement, signaling potential issues in the brain.
  • - A brain biopsy revealed numerous astrocytes with inclusions, and genetic testing found long GGC repeats in the NOTCH2NLC gene, linking them to neuronal intranuclear inclusion disease.
  • - Notably, the MRI findings showed no typical signs of inflammation or ischemia at the enhanced site, while additional tests indicated increased blood flow and a compromised blood-brain barrier as causes of the cerebral swelling.
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We conducted a restrospective cohort study of patients discharged from the emergency department at a tertiary care center with an antimicrobial prescription. More than half of the prescribed antimicrobials were misused and frequently inappropriate for various infectious diseases. In this study, we analyzed the physician-related and environment-related factors predicting misuse.

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