Preventive putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin.

Derangements of neuroimmune, neurotrophic and neurochemical homeostasis have important implications in psychosocial stress-induced psychopathologies. Whether quercetin, a neuroactive compound, protects against psychosocial stress-induced psychiatric disturbances particularly via neurochemical mechanisms remain less well elucidated. Therefore, we further investigated the putative neurochemical as well as other cellular mechanisms of quercetin on social-defeat stress (SDS) model of psychosocial impairments.

Corrigendum to "Chronic consumption of calabash chalk diet impairs locomotor activities and social behaviour in Swiss white Cd-1 mice" [Heliyon 5 (6) (2019) e01848].

[This corrects the article DOI: 10.1016/j.heliyon.

Haematoprotective and red blood cell membrane stabilizing effects of Justicia carnae leaf extracts in sodium nitrate-treated rats.

Objectives Traditionally, Justicia carnae is used in treatment of anaemia. In this study, the haematoprotective effects of ethanol and aqueous leaf extracts of J. carnae were evaluated in sodium nitrate-treated male rats.

Antioxidant potentials and effects on the hematology and osmotic fragility scores of a polyherbal formulation used in Southeast Nigeria.

Background In this study, the hematological and antioxidant potential as well as the osmotic fragility effects of a Nigerian polyherbal formulation were evaluated. Materials and methods A total of 40 fats were divided into four groups of 10 rats each. Group 1 served as the control group, and the rest were assigned increasing daily oral administration of the extract for 28 days.

Chronic consumption of calabash chalk diet impairs locomotor activities and social behaviour in Swiss white Cd-1 mice.

There are safety concerns as regards the consumption of Calabash chalk which is common practice in some localities in Africa and Asia. Calabash chalk contains lead (Pb) and arsenic which are believed to be harmful to the brain and responsible for cognitive dysfunction. It is possible that calabash chalk consumption may affect other neuronal activities in the body such as locomotion and social behaviour.