The Characterisation of Carbapenem-Resistant and in a Teaching Hospital in Malaysia.

: The emergence and dissemination of carbapenem-resistant organisms, particularly and , pose a significant threat to healthcare systems worldwide. This retrospective study aims to characterise carbapenem-resistant (CRAB) and carbapenem-resistant (CRKP) strains in a teaching hospital and to determine the risk factors associated with patients' in-hospital mortality. : A total of 90 CRAB and 63 CRKP were included in this study.

Correction: Naomi et al. Yoghurt-A View from Nutritional Composition and Toxicological Evaluation. 2022, , 1903.

(1) In the original publication [...

A multicentre study to determine the efficacy of flomoxef against extended-spectrum beta-lactamase producing in Malaysia.

Background: The high burden of extended-spectrum beta-lactamase-producing (ESBL)-producing Enterobacterales worldwide, especially in the densely populated South East Asia poses a significant threat to the global transmission of antibiotic resistance. Molecular surveillance of ESBL-producing pathogens in this region is vital for understanding the local epidemiology, informing treatment choices, and addressing the regional and global implications of antibiotic resistance.

Methods: Therefore, an inventory surveillance of the ESBL- (ESBL-EC) isolates responsible for infections in Malaysian hospitals was conducted.

Hidden bugs in a newly opened hospital: the distribution of skin microbiota among healthcare workers in a newly opened teaching hospital.

Skin is a reservoir for millions of micro-organisms, all of which make up the skin microbiota. Hospitals have been identified as a favourable environment for transmitting micro-organisms and thus, it is important to know the distribution of skin microbiota among healthcare workers (HCWs), as such findings may provide baseline information for the distribution of skin microbiota in hospitals..

The role of yoghurt in mitigating high-fat dietary cause of maternal obesity-an experimental study.

Maternal obesity is the key predictor for childhood obesity and neurodevelopmental delay in the offspring. Medicinal plants are considered to be the safe and best option, and at the same time, probiotic consumption during pregnancy provides beneficial effects for both the mother and the child. Current research has shown that () yoghurt is safe to consume and consists of many bioactive compounds that can exert an anti-obesity effect.

Yogurt Supplement in Maternal Obese Dams during Pregnancy Modulates the Body Composition of F1 Generation.

Maternal obesity is a key predictor of childhood obesity and a determining factor for a child's body composition. Thus, any form of maternal nutrition during the gestational period plays a vital role in influencing the growth of the fetus. () yogurt has been found to comprise many bioactive compounds such as tannins, saponins, α-linolenic acid, and 5'-methoxy-bilobate with apocynoside I that could cross the placenta and exhibit an anti-obesity effect.

Phytochemical Analysis and Toxicity Assessment of Yoghurt.

The fruit is native to Malaysia and is known for its many beneficial effects on one's health. Probiotics are well-known for their roles as anti-inflammatory, antioxidant, and anti-tumour properties due to their widespread use. As a result, the purpose of this study was to incorporate the ethanolic extract of into yoghurt and then assess the rodents for any toxicological effects.

Yoghurt-A View from Nutritional Composition and Toxicological Evaluation.

() is a natural tropical plant that possess a wide range of health benefits. Recent discovery proves that extract is able to reduce weight, increase cognitive performance, and ameliorate anxiety and stress hormone. However, this extraction has not been incorporated into yoghurt, and no toxicity studies have been done previously to prove its safety.

Protective effect of in maternal obesity-induced deficit cognitive function of the offspring.

Objectives: Pre-pregnancy obesity is a serious epidemics concern that negatively affects the neurodevelopmental of the offspring. commonly used to enhance weight loss in obesity treatment. This study was aimed to investigate the influence of supplement in obese maternal prior pregnancy on the offspring's bodyweight, lipid metabolism and memory function.

High Level Aminoglycoside Resistance And Distribution Of The Resistance Genes In And From Teaching Hospital In Malaysia.

Background: and are among the predominant species causing hospital-acquired infections. Currently, enterococcal infections are treated using combination therapy of an aminoglycoside with cell-wall active agents, which led to high level aminoglycoside resistance (HLAR) and vancomycin resistance (VRE) among enterococci. The aim of this study was to determine the prevalence of HLAR and the distribution of the resistance genes among clinical and isolates in Malaysia.

A Review of Staphylococcal Cassette Chromosome (SCC) Types in Coagulase-Negative Staphylococci (CoNS) Species.

Coagulase-negative staphylococci (CoNS) are considered low pathogenic organisms. However, they are progressively causing more serious infections with time because they have adapted well to various antibiotics owing to their ability to form biofilms. Few studies have been conducted on CoNS in both, hospital and community-acquired settings, especially in Malaysia.

Impact of signal peptide and transmembrane segments on expression and biochemical properties of a lipase from Bacillus sphaericus 205y.

A total of 97 amino acids, considered as the signal peptide and transmembrane segments were removed from 205y lipase gene using polymerase chain reaction technique that abolished the low activity of this enzyme. The mature enzyme was expressed in Escherichia coli using pBAD expression vector, which gave up to a 13-fold increase in lipase activity. The mature 205y lipase (without signal peptide and transmembrane; -SP/TM) was purified to homogeneity using the isoelectric focusing technique with 53% recovery.