Publications by authors named "Azize Alayli"

Nanoparticles are attracting attention for their potential therapeutic applications, particularly in cancer therapy, underscoring their importance in medicine. Cadmium sulfide nanoparticles, known for their robust catalytic and optical properties, are classified as chalcogenides and show promise for cancer diagnosis and treatment. Neuroblastoma, a common solid tumor in childhood, poses a significant health threat with different outcomes depending on its biological subtype.

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Article Synopsis
  • Nanomaterials, such as ZnO, CuO, and γ-FeO, are used in plant science to enhance growth and protect against environmental stress but their effects on DNA and genome stability in wheat are not fully understood.
  • The study investigates how these nanoparticles affect DNA methylation and genomic instability in mature wheat embryo cultures at varying concentrations (1X, 2X, 3X).
  • Results showed that certain nanoparticle treatments increased DNA polymorphism and cytosine methylation, while higher concentrations reduced polymorphism and indicated hypomethylation, highlighting the potential epigenetic and genotoxic impacts of nanoparticles on wheat.
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Magnesium sulfide nanoparticles (MgS NPs) is a nanomaterial that has an important place in diagnosis, treatment, diagnosis, and drug delivery systems. Neuroblastoma, a type of brain cancer, is an extremely difficult cancer to treat with today's treatment options. This study was carried out to determine the cytotoxic, oxidant, and antioxidant effects on the neuroblastoma cancer line (SH-SY5Y cell line) along with the green synthesis and characterization of MgS NPs structures.

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Neuroblastoma is one of the most widely seen under the age of 15 tumors that occur in the adrenal medulla and sympathetic ganglia. Cisplatin, an antineoplastic drug, is a Platinum-based compound and is known to inhibit the proliferation of neuroblastoma cells. Effective applications of nanoparticles in biomedical areas such as biomolecular, antimicrobial detection and diagnosis, tissue engineering, theranostics, biomarking, drug delivery, and anti-cancer have been investigated in many studies.

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Ca NPs enhanced tolerance of Triticale callus under salt stress by improving biochemical activity and confocal laser scanning analysis, conferring salt tolerance on callus cells. CaO NPs (Ca) are significant components that act as transducers in many adaptive and developmental processes in plants. In this study, effect of Ca NPs on the response and regulation of the protective system in Triticale callus under short and long-salt treatments was investigated.

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In this research, protease enzyme was purified and characterized from milk of Euphorbia amygdaloides. (NH4)2SO4 fractionation and CM-cellulose ion exchange chromatography methods were used for purification of the enzyme. The optimum pH value was determined to be 5, and the optimum temperature was determined to be 60 degrees C.

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In this research, acid phosphatase was purified and characterized from approximately 3000-year-old human bones from archeological excavations. Using anion exchange chromatography, two isoenzymes, TrACP and TsACP, were isolated from the bone. TrACP and TsACP were eluted separately, with a concentration gradient, from a CM-sepharose column.

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