Publications by authors named "Aziz Bulbul"

Background/aim: Ischemia-reperfusion (IR) injury to a part of the body can cause damage to distant organs such as the kidney and heart. This study investigated the protective effects of safranal against IR-induced renal injury.

Materials And Methods: Used in this study were 24 Wistar Albino male rats, which were divided into 3 equal and randomised groups.

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This study was conducted to determine the effects of dietary supplementation of sodium nitroprusside (SNP), a nitric oxide (NO) donor, and NG-nitro-L-arginine methyl ester (L-NAME), an NO synthase inhibitor, on growth performance, organ development, and immunity in broilers. A total of 560 one-day-old mixed-gender broiler chickens (ROSS 308) were divided into one control and seven experimental groups. The experimental groups were fed a basal diet supplemented with 25, 50, 100, and 200 ppm SNP, and 25, 50, and 100 ppm L-NAME in the starter and grower diets.

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Objective: Dental mesenchymal stem cells (MSCs) are potential for use in tissue regeneration in inflammatory diseases due to their rapid proliferating, multilineage differentiation, and strong anti-inflammatory features. In the present study, immunoregulatory and glandular tissue regeneration effects of the dental follicle (DF)MSCs in Sjögren's Syndrome (SS) were investigated.

Methods: Dental follicle (DF) tissues were obtained from healthy individuals during tooth extraction, tissues were digested enzymatically and DFMSCs were cultured until the third passage.

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Introduction: In this study, Anzer propolis, which can only be obtained from the Eastern Black Sea region in Turkey, is studied for its effect on spinal cord ischemia/reperfusion injury.

Methods: A total of 12 healthy male New Zealand White rabbits with an average weight of 3.0 to 3.

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Article Synopsis
  • The study investigates the effects of Nigella sativa L. essential oil (NSE) on thyroid hormones and antioxidant levels in hypothyroidism (HT) and hyperthyroidism (HP) rats over four weeks.
  • NSE treatment at 200 mg/kg resulted in increased total triiodothyronine (TT) and improved antioxidant capacity in hypothyroid rats, while also decreasing TT in hyperthyroid rats.
  • The findings suggest that NSE has potential as a natural remedy to support thyroid health and reduce oxidative stress associated with thyroid disorders.
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Article Synopsis
  • Metabolic diseases like hypothyroidism (HT) are significant health issues, characterized by high TSH levels and low thyroid hormone concentrations, leading to a slower metabolism.
  • The study investigated the effects of essential oils from Myrtus communis L. on oxidative metabolism in a rat model of HT induced by propylthiouracil (PTU), showing that the oils increase antioxidant activity while oxidative status worsens with PTU.
  • The findings suggest that M. communis L. oil could be beneficial for improving oxidative stress in HT, highlighting its potential as a therapeutic option due to its antioxidant properties.
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The aim of this study was to determine the effects of drugs used in the treatment of endotoxaemia on disseminated intravascular coagulation, cytokine levels and adenosine deaminase activities in endotoxaemic rats. Rats were divided into seven groups. Lipopolysaccharide (LPS) was injected into all groups, including the positive control group.

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The aim of this study was to determine the effects of enrofloxacin (ENR), flunixin meglumine (FM) and dexamethasone (DEX) on antioxidant status and organ damage markers in experimentally-induced endotoxemia. Rats were divided into three groups. To induce endotoxemia, lipopolysaccharide (LPS) was injected into all groups, including the positive control.

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This study was designed to determine the acute effects of a single-dose of orally administered doramectin, eprinomectin and selamectin on Syphacia muris infection in rats. Rats, naturally infected with S. muris, were divided into four groups: three different treatment groups (n=7) and one positive control (n=7).

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Article Synopsis
  • The study explored the impact of cytokines IL-1beta, IL-6, and TNF-alpha in chickens affected by amyloid arthropathy, focusing on varying levels of amyloid accumulation.
  • A total of 100 chickens were divided into four groups, with specific treatments (like Vitamin A and methylprednisolone) administered to influence amyloidosis severity after inducing it with Freund's adjuvant.
  • Results indicated a strong correlation between amyloidosis severity, amyloid levels, and IL-1beta, while higher TNF-alpha levels were linked to increased amyloidosis severity, suggesting IL-1beta’s significant role in this condition.
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Clinical, blood, serum biochemistry, and parasitological assessments were performed on four hospitalized dogs, not in good general condition, in a study carried out to determine the prevalence of general parasitic infections. Hematological and biochemical parameters and electrocardiographic recording of the animals were determined during the general clinical examinations. Four dogs were indicated to have been infected with Dirofilaria immitis by using modified Knott's method, and the microfilarial density was determined.

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