enhances pentobarbital-induced sleeping behaviors.

Objective: Sleep disorders are among the most common psychiatric and medical conditions. In the present study, the hypnotic effect of was studied in mice

Materials And Methods: The hydro-alcoholic extract (HAE) of and three fractions of it, namely water fraction (WF), ethyl acetate fraction (EAF), and -hexane fraction (NHF), were intraperitoneally (ip) administrated to mice 30 min before injection of sodium pentobarbital (30 mg/kg, ip). Then, 30 min after administration of HAE, motor coordination (rota-rod test) was evaluated.

Comparing the effects of seed hydro-alcoholic extract, valsartan, and vitamin E on hemodynamic changes, oxidative stress parameters and cardiac hypertrophy in thyrotoxic rats.

The present study compared the effects of ( seed hydro-alcoholic extract, valsartan, and vitamin E on hemodynamic changes, oxidative stress markers and cardiac hypertrophy in a model of thyrotoxicosis. The hyperthyroid state was induced by intraperitoneal injection of levothyroxine (100 µg/kg) for 4 weeks in male adult rats. After 2 weeks, vitamin E (20 mg/kg), valsartan (8 mg/kg), and seed extract (400 mg/kg) were administered in three groups of thyrotoxic rats.

Evaluation of Rheum Turkestanicum in Hexachlorobutadien-Induced Renal Toxicity.

Hexachlorobutadien is nephrotoxic agent in rodents. The mechanism of toxicity includes generation of free radicals, depletion of thiol groups and production of toxic metabolites. Antioxidant compounds may reduce HCBD-nephrotoxicity.

A comparison between the effects of seeds extract and valsartan on echocardiographic and hemodynamic parameters in rats with levothyroxine-induced thyrotoxicosis.

Objective: The aim of the present study was to compare the effects of (Po) seeds extract and those of valsartan on cardiac function in levothyroxine (T)-treated rats.

Materials And Methods: Forty Wistar rats were divided into four groups (n=10): control, levothyroxine (T), T plus valsartan (T-Val) and T plus hydro-alcoholic extract of the seeds (T-Po). Control group received normal saline.

Hypnotic Effect of Red Cabbage () on Pentobarbital-Induced Sleep in Mice.

Objective: The present study was performed to investigate the effect of hydroalcoholic extract of red cabbage and its fractions on sleeping behavior in mice.

Materials And Methods: The extract and its fractions were injected to mice and sleep duration as well as sleep latency were recorded. Furthermore, toxicity of the extract was determined both and .

Kidney stone formation and antioxidant effects of decoction in male Wistar rats.

Objectives: The antioxidant capacity impairs in kidney and urinary bladder of animals with stone disease. Herbal medicine can improve the antioxidant condition of renal tissue. () is a medicinal plant with antioxidative and diuretic properties and different preparations of this plant have shown promising effects in stone disease.

St. John's wort and its component hyperforin alleviate experimental autoimmune encephalomyelitis through expansion of regulatory T-cells.

Multiple sclerosis (MS) is a central nervous system disorder mainly characterized by inflammation, demyelination and axonal injury. Anti-inflammatory agents can be used to ameliorate the disease process. Hypericum perforatum L or St.