Molecular Analysis of Isolates in a 4-year Period.

In the present research, we aimed to determine the characteristics of E. faecalis strains collected from an Iranian Children's Hospital for four years. Sixty-seven E.

Global prevalence and antibiotic resistance in clinical isolates of : a systematic review and meta-analysis.

Introduction: is a little-known environmental opportunistic bacterium that can cause broad-spectrum infections. Despite the importance of this bacterium as an emerging drug-resistant opportunistic pathogen, a comprehensive analysis of its prevalence and resistance to antibiotics has not yet been conducted.

Methods: A systematic search was performed using four electronic databases (MEDLINE via PubMed, Embase, Scopus, and Web of Science) up to October 2019.

Dormancy: Waiting for Insurgency.

Relapse infection usually results from resistance to the antibiotic, acquired genes, or persister cells. Persister cells are formed through mutation, reduced activity or metabolically inactive pathways induced by antibiotics, harassing conditions, low ATP, and malnutrition. These factors provide the ground for bacteria to grow slowly.

Prevalence of Genes Encoding Aminoglycoside-Modifying Enzymes in Clinical Isolates of Gram-Positive Cocci in Iran: A Systematic Review and Meta-Analysis.

Several studies have investigated the genes encoding aminoglycoside-modifying enzymes (AMEs) among gram-positive cocci (GPC) such as , methicillin-resistant (MRSA), coagulase-negative staphylococci (CoNS), and spp. in Iran; however, a comprehensive analysis has not yet been performed. Thus, the present systematic review and meta-analysis was conducted to determine the prevalence of genes encoding AMEs among GPC in Iran.

Antimicrobial resistance pattern, virulence determinants and molecular analysis of Enterococcus faecium isolated from children infections in Iran.

Background: Enterococcus species continues to be an important cause of hospital-acquired infection worldwide. This study was designed to determine the antibiotic resistance profiles, virulence genes and molecular characteristics of Enterococcus faecium strains isolated from an Iranian children hospital in a four-years period.

Results: A total 189 Enterococcus strains, comprising 108 (57%) E.

Status of carbapenem-resistant Acinetobacter baumannii harboring carbapenemase: First systematic review and meta-analysis from Iran.

Carbapenem-resistant Acinetobacter baumannii (CRAB) has been considered as an important pathogen causing hospital-acquired infections thought the world. Class A carbapenemases, class B (metallo-β- lactamases; MBLs) and class D (oxacillinases) are the most important enzymes that are able to hydrolyze carbapenems. There are various reports on the CRAB harboring carbapenemase genes in Iran; but, a comprehensive analysis on the prevalence of CRAB and carbapenemases has not yet been performed.

Clonal relation and antimicrobial resistance pattern of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Enterobacter spp. isolated from different clinical samples in Tehran, Iran.

Introduction: Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples.

Methods: A total of 57 clinical isolates of Enterobacter spp.