Publications by authors named "Aziiz Mardanarian Rosdianto"

Article Synopsis
  • The sap of (Miq). Koidz. contains high levels of chalcones, which are known for their protective effects on kidney cells damaged by cisplatin.
  • The study investigates how sap extract (ASEE) impacts kidney function and specific protein expressions in rats exposed to cisplatin, using doses of 1000 and 1500 mg/kg for 10 days.
  • Results show that ASEE significantly lowers body weight, creatinine, and kidney injury marker levels, indicating potential nephroprotective effects, likely due to its antioxidant and anti-inflammatory properties.
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Article Synopsis
  • Recurrent aphthous stomatitis (canker sores) affects 5-66% of the global population, with a prevalence of 8% in Indonesia and higher rates among male healthcare workers in China at 21.24% and 24.27%.
  • A study investigated the effects of ethanol extract from *L. rhizome* (EKGR) on inflammation markers NF-kappaB-p65 and COX-2 in male Wistar rats, assessing both its effectiveness in promoting healing and its safety using various experimental techniques.
  • The results showed that EKGR significantly inhibits NF-kappaB-p65 and COX-2 expression, demonstrating anti-inflammatory properties, while also being deemed safe with no significant adverse effects
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<b>Background and Objective:</b> Malnutrition and stunting are major unresolved problems in Indonesia. Protein deficiency can cause stunted growth, as well as make physical and cognitive abilities cannot reach their maximum potential. During childhood the need for protein must be fulfilled so that the peak of bone formation during adolescence can be perfect.

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Chronic exposure to elevated levels of pro-oxidant factors may cause structural failings at the mitochondrial DNA level and alteration of antioxidant enzymes (glutathione peroxidase, catalase, and superoxide dismutase). Oxidative stress is an imbalance between the capacity of endogenous non-enzymatic antioxidants (glutathione, alpha-lipoic acid, uric acid, ferritin, metallothionein, melatonin, and bilirubin) and the occurrence of pro-oxidant factors which may lead to the pathogenesis of various diseases that affects the kidneys, pancreas, central nervous system, and cardiovascular system. Therefore, the utilization of medicinal plants with antioxidant activity, e.

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Brown adipose tissue (BAT) and white adipose tissue (WAT) are known to regulate lipid metabolism. A lower amount of BAT compared to WAT, along with adipose tissue dysfunction, can result in obesity. Studies have shown that selenium supplementation protects against adipocyte dysfunction, decreases WAT triglycerides, and increases BAT triiodothyronine (T).

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Fluorescence image-guided surgery (FIGS) can serve as a tool to achieve successful resection of tumour tissues during surgery, serving as a surgical navigator for surgeons. FIGS relies on the use of fluorescent molecules that can specifically interact with cancer cells. In this work, we developed a new model of fluorescent probe based on benzothiazole-phenylamide moiety featuring the visible fluorophore nitrobenzoxadiazole (NBD), namely BPN-01.

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<b>Background and Objective:</b> Contusion in skeletal muscles were common in athletes.<sup> </sup>Contusions usually occur when the tissue is exposed to a rapid and strong compressive force, for example, a direct blow, which usually results in the formation of a hematoma within the muscle. Contusion injuries impair the physiological function of the muscle.

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Materials And Methods: Forty-eight male Wistar rats were divided into anti-inflammatory mechanism study ( = 18) and acute toxicity study ( = 30). The anti-inflammatory mechanism study employed six groups ( = 3), e.g.

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Background And Objective: Flavonols in plants are catalyzed by flavonol synthase (FLS) enzyme. FLS was reported expressed in flowers and fruits, i.e.

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