Placental Dysfunction and Acute Toxoplasmosis: The Role of Melatonin in Relation to Inflammatory Cytokines Interleukin-10 and Interleukin-12.

Objective: The objective of this study was to elucidate the potential role of anti-inflammatory interleukin (IL)-10 and pro-inflammatory (IL-12) cytokines as well as melatonin (MEL) in the development of placental dysfunction in the pregnant women with acquired toxoplasmosis (TOX).

Materials And Methods: This case-control study was carried out at the Department of Clinical Parasitology in teamwork with the Department of Gynecology and Obstetrics, Al-Yarmouk Teaching Hospital, College of Medicine, Al-Mustansiriyah University, Baghdad, Iraq, from September 2018 to February 2019. The recruited patients and healthy controls were allocated into two groups - Group A: pregnant women with acute TOX ( = 45) and Group B: healthy pregnant women ( = 25).

The role of PCSK9 in blood lipids recycling in women with acute toxoplasmosis.

Toxoplasma gondii is intracellular parasite; it is considered one of the most important causes of miscarriage and can inhibit the development of the fetus, especially at the beginning of pregnancy. Host lipids have an important role in the pathogenesis of T. gondii infection.

Ellagic acid-rich Pomegranate extracts synergizes moxifloxacin against methicillin resistance Staphylococcus aureus (MRSA).

Objective: To elucidate the anti- Methicillin resistance Staphylococcus aureus (MRSA) effect of pomegranate alone and in combination with moxifloxacin fluoroquinolone.

Methods: A total of five clinical isolates of MRSA (ATCC 43300) were used in the study. Disc diffusion method was used to determine the anti-MRSA effect of pomegranate and/or moxifloxacin by using Mueller-Hinton agar.

Are alterations in melatonin and inflammatory cytokine serum levels linked with recurrent abortion in pregnant women with acute toxoplasmosis: The interacted nexus.

Objective: To investigate melatonin serum level and inflammatory biomarkers in acute toxoplasmosis in pregnant women with recurrent abortions.

Methods: The case-control study was conducted at the Department of Parasitology, together with the Department of Obstetrics, Al-Yarmouk teaching hospital, Baghdad Iraq, from September 2018 until February 2019. Included were 60 pregnant women in first trimester with acute toxoplasmosis (n=28) or without toxoplasmosis (n=32) and with the history of recurrent abortions with a control group of healthy pregnant women (n=25).

Endothelial dysfunction in acute acquired toxoplasmosis.

Background: Acute toxoplasmosis (AT) which is caused by () leads to induction of pro-inflammatory and/or oxidative stress changes through activation of host immune response. Therefore, the endeavor of the present study was to assess endothelial dysfunction(ED) and oxidative stress in patients with acute toxoplasmosis.

Methods: This study involved 21 patients with AT compared with 20 healthy controls.