Publications by authors named "Azevedo E"

Introduction: Vocal symptoms are frequent in patients with coronavirus disease 2019 (COVID-19) and may occur during or after infection.

Objective: To conduct a descriptive review on the topic "dysphonia and COVID-19" in order to alert specialists to these symptoms associated with the virus and sequelae.

Methodology: A literature review was carried out in the main databases: Web of Science, PubMed, Google Scholar, and Scopus, between April 2020 and April 2024 using descriptors that related COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) to voice disorders.

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Selenium is one of the most important trace element micronutrients for the global biota, mainly due to its role in protecting against oxidative stress. However, this element can become toxic when present at concentrations slightly higher than those needed for metabolic purposes. It can be transferred through the food chain toward higher trophic levels, with bioaccumulation and biomagnification leading to possible toxicity.

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  • - The Oropouche virus (OROV), part of the Orthobunyavirus species, is an arthropod-borne zoonotic virus primarily transmitted by biting midges, causing significant outbreaks in humans, especially since the 1970s in the Amazon basin.
  • - Since 2022, OROV outbreaks have spread more widely across Brazil and South America, with cases being reported as far away as Cuba, Italy, Spain, the USA, and Germany, establishing community transmission in all areas of Brazil.
  • - Recent studies in Pernambuco state recovered and characterized two OROV isolates from the ongoing outbreak, revealing evidence of sustained transmission and highlighting the need for further research on the virus's transmission cycles to implement effective control
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  • This paper outlines a protocol for a systematic review and meta-analysis to assess the effectiveness and safety of pembrolizumab, either alone or with other treatments, in adult women with cervical carcinoma starting from stage IB2.
  • The review will follow PRISMA-P guidelines and search multiple databases and grey literature sources, focusing on randomized clinical trials that evaluate pembrolizumab's impact on cervical cancer outcomes.
  • The results will be analyzed and presented to provide quality evidence that can help inform clinical decisions regarding the use of pembrolizumab in this patient population.
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Objectives: To analyze the immediate impact of vocal demand, probability of dysphonia, and performance aspects in amateur protestant singers.

Methods: Cross-sectional, analytical study, with 76 amateur singers from a protestant church, 60 women and 16 men. All participants responded to a sociodemographic and performance questionnaire, the Evaluation of the Ability to Sing Easily for Brazil (EASE-BR), and the Dysphonia Screening Tool (DST-Br).

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Introduction: Chronic Chagas cardiomyopathy (CCC), the most severe clinical condition of Chagas disease, often leads to a reduction in functional capacity and the appearance of symptoms such as fatigue and dyspnea on exertion. However, its determinant factors remain unclear. We aimed to evaluate the peak oxygen consumption (VO) in patients with CCC and identify its determining factors.

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We investigated the occurrence and the environmental risk of eight contaminants of emerging concern (CECs; acetaminophen, naproxen, diclofenac, methylparaben, 17β-estradiol, sulfathiazole, sulfadimethoxine, and sulfamethazine) in three Brazilian water bodies, namely, the Monjolinho River Basin (São Paulo State), the Mogi Guaçu River (São Paulo State), and the Itapecuru River (Maranhão State) in three sampling campaigns. The CECs were only quantified in surface water samples collected at the Monjolinho River Basin. Acetaminophen, naproxen, and methylparaben were detected in the range of <200 to 575.

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Objectives: Giant cell arteritis (GCA) is the main systemic vasculitis in individuals aged ≥ 50 years. Color Doppler ultrasound (CDS) has an established role in GCA diagnosis and management. This study aims to assess the clinical characteristics associated with a positive CDS evaluation and the impact of additional axillary artery examination on diagnostic sensitivity.

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Objective: To compare and correlate musical performance anxiety (MPA) and vocal self-perception among amateur evangelical singers, focusing on the interaction between anxiety and aspects of performance in this sample.

Method: This study employed a cross-sectional and quantitative approach, involving 75 amateur gospel singers from evangelical churches, aged between 18 and 59 years. Data collection included the administration of a sample identification and characterization questionnaire, the Brazilian Portuguese version of the Kenny Music Performance Anxiety Inventory (K-MPAI), and the Singing Voice Handicap Index (S-VHI).

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  • A significant portion (26.9%) of patients hospitalized for neurologic disorders in Portugal also had psychiatric comorbidities, highlighting an often overlooked aspect of their care.
  • Most of these patients were younger and had longer hospital stays but lower in-hospital mortality rates compared to those without psychiatric issues.
  • Common psychiatric comorbidities included cognitive disorders, alcohol-related disorders, and mood disorders, with epilepsy/seizures having the highest association with psychiatric conditions.
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Background: In recent years, dental pulp stromal cells (DPSCs) have emerged as a promising therapeutic approach for Parkinson's disease (PD), owing to their inherent neurogenic potential and the lack of neuroprotective treatments for this condition. However, uncertainties persist regarding the efficacy of these cells in an undifferentiated state versus a neuronally-induced state. This study aims to delineate the distinct therapeutic potential of uninduced and neuronally-induced DPSCs in a rodent model of PD induced by 6-Hydroxydopamine (6-OHDA).

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We examined the relation between transcranial Doppler (TCD) markers of cerebral blood flow regulation and cognitive performance in hypertension (HT) patients to evaluate the predictive value of these markers for cognitive decline. We assessed dynamic cerebral autoregulation (dCA), vasoreactivity to carbon dioxide, and neurovascular coupling (NVC) in the middle (MCA) and posterior (PCA) cerebral arteries of 52 patients. Neuropsychological evaluation included the Montreal Cognitive Assessment and tests covering attention, executive function, processing speed, and memory.

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Purpose: To analyze self-perceived vocal symptoms and discomfort in amateur church singers and compare them between genders and church types.

Methods: It was a quantitative cross-sectional study involving 99 amateur church singers aged between 18 and 59years. Data collection was carried out through the completion of a sociodemographic questionnaire, the Voice Symptom Scale (VoiSS), and the Vocal Tract Discomfort Scale (VTDS).

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Known for its antioxidant properties, Araucaria angustifolia bracts extract was encapsulated using hydrodynamic electrospray ionization jetting within calcium alginate cross-linked hydrogel beads with varying contents of modified pinhão starch. The rheological properties of the dispersions and analysis of the physicochemical and digestive properties of encapsulated beads were studied. The results demonstrated that dispersions containing starch exhibited higher viscosity and reduced compliance values, indicating samples with stronger, more compact, and stable structures that are less susceptible to deformation.

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  • The study conducts a systematic review of costs associated with hospital readmissions for stroke patients, highlighting the variability in expenses reported across different countries and types of strokes.
  • A total of 44 studies were included, revealing that, particularly in the UK and USA, post-stroke readmission costs can represent a significant percentage of direct and total healthcare costs in the first year after discharge.
  • The findings emphasize the need for improved data standardization and the identification of factors influencing readmission costs to better inform healthcare policymakers and providers about the economic burden of stroke readmissions.
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 To provide an overview on education, training, practice requirements, and fields of application of neurosonology in Europe and beyond.  National representatives and experts in neurosonology were surveyed regarding neurosonology requirements and practice in their countries. Descriptive statistics were used to report the data.

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Objective: Neurovascular coupling (NVC) represents the increase in regional blood flow associated with neural activity. The aim here was to describe a new approach to non-invasive measurement of NVC by spectral analysis of the cerebral blood flow velocity (CBFV) with transcranial Doppler.

Methods: In a sample of 20 healthy participants, we monitored systolic CBFV in the left posterior cerebral artery (PCA) during off (eyes closed) and on (flickering checkerboard) periods.

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Dementia has been faced with significant public health challenges and economic burdens that urges the need to develop safe and effective interventions. In recent years, an increasing number of studies have focused on the relationship between dementia and liver and pancreatic metabolic disorders that result in diseases such as diabetes, obesity, hypertension and dyslipidemia. Previous reports have shown that there is a plausible correlation between pathologies caused by hepatopancreatic dysfunctions and dementia.

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Introduction: We investigated the burden of microembolic signals (MES) in patients with acute ischaemic stroke (AIS) and atrial fibrillation (AF), assessing their impact on functional outcomes.

Patients And Methods: This multicentre international prospective cohort study involved patients with AIS and either a known or newly diagnosed anticoagulant-naïve AF. All centres utilised the same transcranial Doppler machine for 1-h monitoring with bilateral 2 MHz probes within 24 h of symptom onset.

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Back mobility is a criterion of well-being in a horse. Veterinarians visually assess the mobility of a horse's back during a locomotor examination. Quantifying it with on-board technology could be a major breakthrough to help them.

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  • The study assessed the effects of laser therapy using different wavelengths on two women with different skin types and hair locations.
  • After 45 days, surgeries were performed, revealing that untreated areas had active hair follicles in the anagen phase, while treated areas showed hair follicles in the telogen phase, indicating hair loss.
  • The findings confirmed that laser treatment effectively targets various skin phototypes and hair thickness, enhancing the hair removal process through the observation of cell death and growth markers.
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Hydrotherapy has been utilized in horse rehabilitation programs for over four decades. However, a comprehensive description of the swimming cycle of horses is still lacking. One of the challenges in studying this motion is 3D underwater motion capture, which holds potential not only for understanding equine locomotion but also for enhancing human swimming performance.

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