Assessment of Essential and Toxic Element Levels in the Toenails of Children with Autism Spectrum Disorder.

Autism spectrum disorder (ASD) has become a global public health concern, impacting the quality of life. The question of gene-environment interaction in the emergence of ASD remains a subject of ongoing debate, and exploring its pathophysiology is thoroughly related to metals as a risk factor. Therefore, this study aims to assess the levels of toxic (Al, Cd, Hg, and Pb) and essential (Cr, Mn, Fe, Ni, Cu, Zn, and Se) elements in toenail samples collected in children with ASD and neurotypical children, by ICP-MS.

Phenotype and molecular characterization of Wilson's disease in Morocco.

Background And Study Aims: In Morocco the prevalence of Wilson disease (WD) and the spectrum of mutations are not known. The aim of the present study was to estimate the prevalence of WD in Morocco, to evaluate the phenotype among a large cohort of WD patients, and to characterize ATP7B variants in a subgroup of WD patients.

Patients And Methods: We collected data from 226 patients admitted to five university hospital centers in Morocco between 2008 and 2020.

Iron deficiency and cognitive impairment in children with low blood lead levels.

Background: The relationship between iron deficiency (ID) and children's neurocognitive functions has attracted the interest of the scientific community, particularly among those living at the lead-contaminated sites. Thus, the current paper aims at evaluating the association between ID and neurocognitive performance of school children living in a mining area (CMA) in comparison with a control group (CG).

Methods: he study involves 90 school children aged from 6 to 10 years old.

Hair Trace Elements and Mineral Content in Moroccan Children with Autism Spectrum Disorder: a Case-Control Study.

The prevalence of autism spectrum disorder (ASD) around the world continues to increase while the pathophysiology remains insufficiently elucidated. Genetics, environment, and epigenetic changes are often implicated. Abnormal level in trace elements and minerals is among environmental factors assumed to be involved.

Effects of Imbalance in Trace Element on Thyroid Gland from Moroccan Children.

The major environmental factor that determines goiter prevalence is iodine status. However, other trace elements like selenium and zinc can influence the thyroid function. Hair samples (n = 68) were collected from goitrous and non-goitrous children aged 8-12 years living in the area of Al Haouz Marrakech-(Morocco).

Lead and aluminium levels in infants' hair, diet, and the local environment in the Moroccan city of Marrakech.

In order to assess the contamination burden of infants from the city of Marrakech (Morocco), hair lead and aluminium concentrations were studied in a sample of 573 infants, aged 0 to 12 months, and correlated with the infants descriptors such as age, gender and the parents occupations. Moreover, the two metals were measured in the local environment (soil, drinking water) and in the food commonly used during weaning. The mean values in children's hair are 6.

Trace element level in infant hair and diet, and in the local environment of the Moroccan city of Marrakech.

A sample of 573 infants (aged 0 to 12 months) from the Moroccan city of Marrakech was studied in order to determine the level of Pb and Al contaminations. Mean values of Pb and Al in children's hair were 6.6 and 9.