Modulates Murine and Human Beta Defensin-1 during Vaginitis.

Vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) are two forms of a disease caused by spp. β-defensin (BD) is one of the most important families of antimicrobial peptides in the female genital tract and includes molecules that exert essential local functions as antimicrobial and PMN chemoattractant peptides. However, the information on their role during murine and human VVC and RVVC is limited.

Frequency, virulence factors and antifungal susceptibility of Candida parapsilosis species complex isolated from patients with candidemia in the central region of Argentina.

Purpose: Our objectives were to report species distribution and survival of patients with candidemia in Argentina's central region and to establish the prevalence of C.parapsilosis sensu lato species, their virulence factors and their antifungal susceptibility profiles.

Methods: Yeasts isolated from bloodstream infections in Córdoba (Argentina) (n=35) were molecularly identified.

[Candida lipases: a review on biochemical, molecular and pathogenic aspects].

In the last half century there was a significant increase in the incidence of fungal infections being likely to become a global health priority. The sophisticated degree of host-Candida interaction is the product of different virulence strategies used by the fungus to invade the tissues and the various defense mechanisms that it develops to control it. There is a significant amount of literature that indicates that this opportunistic commensal fungus has components that can be considered virulence factors related to the stage of the infectious process.

Study of virulence factor of Candida species in oral lesions and its association with potentially malignant and malignant lesions.

Objective: The aim of this study was to explore the association between malignant and premalignant lesions and the virulence factor profile of Candida spp. recovered from different oral lesions.

Design: Candida spp.

Comparative study of preventive protocols in children at high cariogenic risk.

The aim of this study was to compare the efficacy of two preventive protocols -fluoride gel (F) alone or combined with chlorhexidine varnishes (CHX) - on sialochemical, clinical and microbiological parameters in a group of children at high cariogenic risk Two therapeutic-preventive protocols were applied in 73 children at high cariogenic risk (average age 6.2 +/- 1.4 years old) and clinical parameters (simplified oral hygiene index: OHI-S; decayed, missing and filled teeth: dmf index; sugar intake and exposure to fluoride), as well as sialochemical parameters (salivary pH and flow, buffer capacity) and microbiological parameters (CFU/mg of dental biofilm of Streptococcus mutans group) were recorded and correlated before and after the protocols.

Oral ecosystem alterations in celiac children: a follow-up study.

Objective: The aims of this work were (1) to assess the oral health status of children with celiac disease (CD) with or without compliance with a gluten-free diet and in non-celiac children in a follow-up study and (2) to identify oral ecosystem changes that could be used as non-invasive monitoring methods for CD patients.

Study Design: An 18-month follow-up study in children of both genders, who were 4-12 years old during the study period, was performed. Decayed-missing-filled in temporary (dmft) and permanent teeth (DMFT), enamel alterations, oral hygiene, and gingival index were measured.

Antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on Candida albicans.

Objective: The aim of this work was to assess the antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on virulence factors of Candida albicans.

Study Design: Ten isolated strains of Candida albicans obtained from 10 patients with oral candidiasis and a collection strain of C. albicans were treated with antifungal agents in different concentrations or combinations of them.

Alterations of the oral ecosystem in children with celiac disease.

Unlabelled: The aim of this work is to evaluate the alterations of the oral ecosystem in symptomatic children with celiac disease (CD), to establish a particular pattern of oral markers that can be used as presumptive diagnosis of CD.

Material & Methods: A sample of n=52 children with CD diagnosis according to the modified criteria of the European Society of Pediatric Gastroenterology and Nutrition (ESPGAN), 1990, was studied. A dental clinical evaluation of soft and hard tissues was performed.

Evaluation of clinical dental variables to build classifiers to predict celiac disease.

Objective: The aim of this study was to evaluate the use of salivary variables to build statistical models for predicting celiac disease in symptomatic children.

Materials And Methods: The study group consisted of 52 children with celiac disease diagnosed by bowel biopsy, grade III or IV (4 to 12 years old, both sexes) and 23 healthy children as a control group. A logistic regression model was applied to evaluate an individual's belonging to one group or another.

Effect of the high molecular weight chitosan and sodium alginate on Candida albicans hydrophobicity and adhesion to cells.

Unlabelled: The aim of the present paper is to evaluate the effect of the high molecular weight chitosan (HMWC) and of sodium alginate (NaAL) on surface hydrophobicity of Candida albicans and on adhesion of the yeast to epithelial cells and fibroblasts of different proceeding. For this study, a collection strain and seven isolates of C. albicans from saliva (patients with denture stomatitis) were grown in Sabouraud glucose agar supplemented with HMWC or NaAL or in absence of them (control).

[High molecular weight chitosan and sodium alginate effect on secretory acid proteinase of Candida albicans].

The effect of high molecular weight chitosan (HMWCh) and sodium alginate (NaAL) on acid proteinase secretion of Candida albicans (one of culture collection and five isolates) was evaluated. The secretion of acid proteinase was induced in the presence and the absence of these polymers in different concentrations and their enzymatic activity was determined. HMWCh and NaAL significantly diminished the enzymatic activity (>76% for the collection strains and > 89% for the isolates, p < 0.

Evolution of saliva and serum components in patients with oral candidosis topically treated with Ketoconazole and Nystatin.

The present study involves the analysis of some saliva components (SC) and serum components in patients with oral candidosis topically treated with Ketoconazole 2% (K) or Nystatin 100,000 IU (N). Twenty-four male and female patients, age range 39-82 years, were included in the study. A double-blind study was undertaken in which the patients were divided into 2 treatment groups.

Evaluation of serum and saliva components in candidosis patients.

The serum and saliva components of 36 chronic Candidosis patients, both male and female, ages 38-82 who attended the Department of Clinical Stomatology were studied. Total Mucous Lesion Index (TMLI) and salivary flow rate were assessed. The following parameters were evaluated: iron bound protein, unsaturated iron binding capacity, peroxidase activity, protein content, OSCN-, SCN-, IgAs, Candida and St.

Effects of xylitol, sorbitol and fluoride mouthrinses on glucose clearance in adolescents.

The present work describes and analyzes the results of a randomized clinical trial on 98 healthy adolescents (age 18 +/- 0.7 years) in order to evaluate the effects of a 14 days treatment with mouthrinses containing xylitol (0.2%; 0.

[[Effects of local treatment with sodium fluoride mouthrinse on peroxidase and hypothiocyanite saliva levels in adolescent]/].

The present work describes and analyzes the results of a randomized clinical trial on adolescents (age 18.2 +/- 0.6) carried out in order to evaluate the effects of a twice daily mouthrinse application containing xylitol, sorbitol, sacarine, ciclamate, aspartame, chlorhexidine, hexetidine or NaF for 14 days on amylase, peroxidase, thiocyanate, hypothiocyanite, secretory IgA and total proteins in whole saliva.

Bucodental health condition in patients with Down syndrome of Cordoba City, Argentina.

The oral health condition of children and youngsters with Down Syndrome (DS) was evaluated on a sample of 86 mongolic subjects ages 3 to 19, both sexes, residents in the city of Córdoba (Argentina), and compared with control groups. Those persons were attended special educational institutions for the care of that type of disabled individuals. In every age group, the dmf-t and dmf-s indexes were higher in the mongolic children than in the control population, while from the age of 10 onwards the DMF-T and DMF-S of the control population were higher than those of the DS individuals.

[Dental health status of students living in places supplied with drinking water of very high and very low levels of fluorides].

The results of a cross sectional epidemiological survey for the purpose of evaluating the state of dental health of schoolchildren (aged 6-7 and 12-13) living in Sampacho and Porteña, two towns in the Province of Córdoba (Argentina), supplied with drinking water containing quite different levels of fluoride, are described and analized. In Sampacho, F- level is 9.05 mg/l.