The association of cytokine levels and postnatal factors with retinopathy of prematurity.

Purpose: Prematurity has been known to trigger several cellular pathways, leading to the clinical occurrence of retinopathy of prematurity (ROP). This study compared the levels of a panel of serum cytokines in premature infants with and without ROP.

Methods: This is a prospective observational study.

The Association between Serum Bilirubin and Kernicterus Spectrum Disorder: A Systematic Review and Meta-Analysis.

Background: Total serum bilirubin (TSB) is used in managing neonates with jaundice, but clear evidence on its association with major outcomes is lacking.

Objectives: We evaluated the association between TSB and kernicterus spectrum disorder (KSD).

Methods: We searched PubMed, EMBASE, and CENTRAL till July 2021.

Magnetic Non-invasive Auricular Acupuncture During Eye-Exam for Retinopathy of Prematurity in Preterm Infants: A Multicentre Randomized Controlled Trial.

Eye exam for Retinopathy of prematurity (ROP) is a painful procedure and pharmacological analgesia might be ineffective. We hypothesized that magnetic auricular acupuncture (MAA) compared to placebo will decrease pain during ROP exam in preterm infants. Multicentre randomized controlled trial conducted in three hospitals (Australia, Canada, and Malaysia).

Paediatric Palliative Care during the COVID-19 Pandemic: A Malaysian Perspective.

Malaysia had its first four patients with COVID-19 on 25 January 2020. In the same week, the World Health Organization declared it as a public health emergency of international concern. The pandemic has since challenged the ethics and practice of medicine.

Preterm Infant Outcomes after Randomization to Initial Resuscitation with FiO 0.21 or 1.0.

Objective: To determine rates of death or neurodevelopmental impairment (NDI) at 2 years corrected age (primary outcome) in children <32 weeks' gestation randomized to initial resuscitation with a fraction of inspired oxygen (FiO) value of 0.21 or 1.0.

Cost is an important factor influencing active management of extremely preterm infants.

Aim: The attitudes of neonatologists towards the active management of extremely premature infants in a developing country like China are uncertain.

Methods: A web-based survey was sent to neonatologists from 16 provinces representing 59.6% (824.

What does the world think of ankyloglossia?

Aim: The diagnosis of tongue-tie (or ankyloglossia) has increased more than 10-fold in some countries. Whether this is a global phenomenon or related to cultural and professional differences is uncertain.

Methods: An online survey in English, Japanese, Chinese and Spanish was disseminated between May and November 2016 via 27 international professional bodies to >30 clinical professions chosen a priori to represent occupations involved in the management of neonatal ankyloglossia.

Targeted Oxygen in the Resuscitation of Preterm Infants, a Randomized Clinical Trial.

Background And Objectives: Lower concentrations of oxygen (O) (≤30%) are recommended for preterm resuscitation to avoid oxidative injury and cerebral ischemia. Effects on long-term outcomes are uncertain. We aimed to determine the effects of using room air (RA) or 100% O on the combined risk of death and disability at 2 years in infants <32 weeks' gestation.