Publications by authors named "Azam Shafaei"
Article Synopsis
- The study assessed the humoral immune response to COVID-19 vaccines in individuals infected with HTLV-1 in northeastern Iran over nearly a year.
- It involved 86 HTLV-1 positive individuals and 90 matched seronegative controls, revealing that those with HTLV-1 had significantly lower antibody responses to the vaccines, even after 2 or 3 doses.
- The findings suggest that people living with HTLV-1 demonstrate a reduced immune response to COVID-19 vaccination, particularly among those displaying specific symptoms of the disease.
Background: Sexually transmitted infections (STIs) are one of the world's most severe health challenges. The existence of STIs such as human papillomavirus (HPV) might cause cervical cell changes leading to cervical cancer.
Objective: This study aims to assess the association of STIs with cervical cytological abnormalities and genital warts among women in northeastern Iran.
Background: In HTLV-1-associated malignant disease, adult T-cell leukaemia/lymphoma (ATLL), the interaction of virus and host was evaluated at the chemokines gene expression level. Also, IL-1β and Caspase-1 expressions were evaluated to investigate the importance of pyroptosis in disease development and progression.
Methods And Results: The expression of host CCR6 and CXCR-3 and the HTLV-1 proviral load (PVL), Tax, and HBZ were assessed in 17 HTLV-1 asymptomatic carriers (ACs) and 12 ATLL patients using the reverse transcription-quantitative polymerase chain reaction (RT-qPCR), TaqMan method.
Acute intoxication with diazinon (DZN) as a pesticide causes mortality and morbidity annually. This study shows the impact of sub-acute toxicity of DZN 20 mg/kg and the protective activities of chrysin (CH) as a flavone under the flavonoids family (12.5, 25 and 50 mg/kg) were assessed on BALB/c mouse immune system.
View Article and Find Full Text PDFSerum Progranulin Levels in Type 2 Diabetic Patients with Metabolic Syndrome.
Rom J Intern Med
December 2016
Introduction: The role of progranulin in individuals with metabolic syndrome is not exactly clear.We aimed to assess the serum level of progranulin in type 2 diabetic patients with and without metabolic syndrome and compare them with healthy controls.
Methods: The study included 60 patients with type 2 diabetes and 30 healthy individuals as control groups.