Prevalence and Associated Factors of Cataract, Cataract Surgery and Postoperative Outcome in an Old Population in Russia: The Ural Very Old Study.

Purpose: To assess prevalence of cataract and cataract surgery in a very old population in Russia.

Design: Population-based study.

Participants: The Ural Very Old Study included 1526 (81.

Atrial fibrillation and flutter and ocular diseases. The Ural eye and medical study and the Ural very old study.

Purpose: To assess associations between atrial fibrillation/atrial flutter (AF) and ocular parameters and diseases.

Methods: The population-based Ural Eye and Medical Study (UEMS) and the Ural Very Old Study (UVOS) included 4894 individuals (age: 40+ years) and 835 individuals (age: 85+ years), respectively.

Results: In the UEMS, AF prevalence (80/4894; 1.

Unintentional injuries and falls in populations in Russia. The Ural eye and medical study and the Ural very old study.

Background: To explore the prevalence of self-reported unintentional injuries and falls (UIFs) in medium-aged and old populations in Russia and factors associated with them.

Methods: Two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)) were carried out urban and rural areas in Bashkortostan/Russia. They consisted of 5899 individuals (age: 40+ years) and 1526 participants (age: 85+ years), respectively.

Intraocular pressure and its determinants in a very old population. The ural very old study.

Purpose: To explore intraocular pressure (IOP) and its associated parameters in an aged population.

Methods: The epidemiologic Ural Very Old Study (UVOS) conducted in Bashkortostan/Russia included 1526 participants with an age of ≥85 years. Besides a whole series of ocular and systemic examinations, IOP was determined applying non-contact tonometry.

Prevalence and Associations of Keratoconus Among Children, Adults, and Elderly in the Population-Based Ural Eye Studies.

Purpose: To estimate prevalence and associations of keratoconus in populations in Russia with an age from childhood to seniority.

Methods: The study population consisted of the cohorts of 3 population-based studies performed in urban and rural areas within the same geographical region in Bashkortostan/Russia: the Ural Children Eye Study (UCES; age = 6-18 y; n = 4890), the Ural Eye and Medical Study (UEMS; age = >40 y; n = 5314), and the Ural Very Old Study (UVOS; age = >85 y; n = 651). Based on Scheimflug imaging, keratoconus was defined by a keratometric reading of ≥48 diopters (D) in any eye.

Anterior chamber depth and angle and associations in a pediatric and adult population in Russia.

Purpose: To investigate the normative data of anterior chamber depth (ACD) and angle (ACA) and their associations in multiethnic cohorts spanning three generations in Russia.

Methods: The study cohort included the participants of three population-based studies performed in urban and rural Bashkortostan/Russia: The Ural Eye and Medical Study (UEMS; age:40+ years), Ural Children Eye Study (UCES; age:6-18 years), and Ural Very Old Study (UVOS; age:85+ years). Using Scheimflug camera-based anterior chamber imaging, we measured ACD and ACA as part of a comprehensive ophthalmological and systemic examination.

Associations between axial length, corneal refractive power and lens thickness in children and adolescents: The Ural Children Eye Study.

Purpose: To assess relationships between ocular biometric parameters in dependence of age and sex in children and adolescents.

Methods: In the Ural Children Eye Study, a school-based cohort study, 4933 children underwent an ophthalmological and general examination.

Results: Complete biometric measurements were available for 4406 (89.

Prevalence and associated factors of myopia in children and adolescents in Russia: the Ural Children Eye Study.

Background: To assess the prevalence of myopia and the distribution of ocular axial length as surrogate for myopic refractive error in school children in a population in Russia.

Methods: The Ural Children Eye Study, a school-based case-control study, was conducted in Ufa/Bashkortostan/Russia from 2019 to 2022 and included 4933 children (age: 9.7±2.

Myopic axial elongation in school children and the COVID-19 lockdown in Russia: The Ural Children Myopia Study.

Background: To explore an influence of the COVID-19-related lockdown on ocular axial elongation in school children in Russia.

Methods: The participants of the school-based Ufa Children Myopia Study in Ufa/Russia underwent, at baseline in 2019/2020 before the COVID-19 outbreak and after a COVID-19-related lockdown, a detailed interview and ophthalmological examination including laser interferometric biometry for axial length measurement.

Results: The study included 461 children (age:10.

Prevalence and associations of dry eye disease and meibomian gland dysfunction in the ural eye and medical study.

To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a population in Russia. The population-based Ural Eye and Medical Study was conducted in an urban and rural region in Bashkortostan/Russia and included 5899 (80.5%) out of 7328 eligible persons, aged 40 + years.

Hand grip strength and ocular associations: the Ural Eye and Medical Study.

Purpose: To explore the associations between hand grip strength (HGS) and ocular parameters and diseases.

Design: Population-based cohort study.

Methods: Participants of the Ural Eye and Medical Study, including 5899 (80.

Cognitive impairment in the population-based ural very old study.

Background: Despite its marked importance in public health, the prevalence of cognitive impairment (CI) and its associated factors have only rarely been examined in old populations in general or in Russia at all.

Objective: To assess CI prevalence and its determinants in a very elderly population in Russia.

Materials And Methods: The population-based Ural Very Old Study, conducted in rural and urban region in Bashkortostan/Russia, included 1,526 (81.

Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study.

To determine the prevalence of osteoarthritis and its associated factors in populations from Russia. The population-based Ural Eye and Medical Study (UEMS) and the population-based Ural Very Old Study (UVOS) were conducted in a rural and urban region in Bashkortostan/Russia and included participants aged 40+ and 85+ years, respectively. As part of a detailed systematic examination, we assessed the osteoarthritis prevalence in an interview including questions on the self-reported presence of osteoarthritis, the joints affected and osteoarthritis-related pain-relieving therapy taken.

Safety and tolerability of intravitreal cetuximab in young and adult rabbits.

To assess safety and tolerability of intraocularly applied cetuximab as epidermal growth factor receptor antibody, we conducted the experimental study which consisted of groups of adult rabbits (body weight: 2.4 kg) and young rabbits (body weight: 1.6 kg).

Prevalence of non-alcoholic fatty liver disease in the Russian Ural Eye and Medical Study and the Ural Very Old Study.

Information about prevalence and associated factors of non-alcoholic fatty liver disease (NAFLD) has been scarce for the Russian, Eastern European and Central Asian world region. We assessed prevalence and associated factors of NAFLD in two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)), which were conducted in rural and urban regions in Bashkortostan/Russia and included participants aged 40 + years and 85 + years, respectively. Defining NAFLD by an absence of regular alcohol consumption, and by abnormally high alanine transaminase (ALT) and aspartate transaminase (AST) concentrations or an AST/ALT ratio of > 1.

Concurrent vision and hearing impairment associated with cognitive dysfunction in a population aged 85+ years: the Ural Very Old Study.

Objective: To assess the prevalence of vision impairment, hearing impairment and dual sensory impairment (DSI) as combination of vision and hearing impairment, in association with cognitive dysfunction in a population aged 85+ years.

Methods: The cross-sectional population-based Ural Very Old Study, conducted in rural and urban Bashkortostan, Russia, between 2017 and 2020, included a detailed ocular and systemic examination with assessment of moderate to severe vision impairment (MSVI)/blindness (best-corrected visual acuity <6/18), moderate to severe hearing loss (MSHL) and cognitive function.

Setting: A rural and urban area in Bashkortostan, Russia.

Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study.

Purpose: To examine prevalence and associated factors of the metabolic syndrome (MS) in populations in Russia.

Methods: Two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)) were conducted in rural and urban regions in Bashkortostan/Russia and included participants aged 40+ years and 85+ years, respectively.

Results: Out of 5895 UEMS participants, 1572 individuals had MS (prevalence:26.

Prevalence and determinants of reticular pseudodrusen in the Russian Ural Eye and Medical Study.

Purpose: To assess the prevalence of reticular pseudodrusen (RPD) and their determinants.

Methods: The Population-based Ural Eye and Medical Study conducted in Bashkortostan/Russia included 5899 participants aged 40+ years. Presence of RPDs was assessed on conventional colour fundus photographs, red-free fundus images and optical coherence tomographic images.

Macular pigment optical density and its determinants in a Russian population: the ural eye and medical study.

Purpose: To assess the macular pigment optical density (MPOD) and its associations with ocular and systemic parameters and diseases.

Methods: The population-based study Ural Eye and Medical Study included 5899 (80.5%) out of 7328 eligible individuals.

Prevalence and Associated Factors of Diabetic Retinopathy in a Russian Population. The Ural Eye and Medical Study.

Aim: To assess prevalence and associated factors of diabetic retinopathy (DR) in a Russian population.

Methods: Out of 7328 eligible individuals, the population-based cross-sectional Ural Eye and Medical Study included 5899 (80.5%) individuals aged 40+ years, who underwent a detailed medical and ophthalmological examination.

Ankle-brachial index and ocular diseases in a Russian population.

Background: To assess potential associations between the ankle-brachial blood pressure index (ABI) and ocular disorders.

Methods: In the population-based cross-sectional Russian Ural Eye and Medical Study including 5,899 (80.5%) out of 7328 eligible participants aged 40+ years, the participants underwent a series of ocular and medical examinations including measurement of ABI.

Axial length and its associations in the Ural Very Old Study.

To assess the distribution of axial length as surrogate for myopia and its determinants in an old population, we performed the Ural Very Old Study as a population-based cohort study. Out of 1882 eligible individuals aged 85 + years, the Ural Very Old Study performed in an urban and rural region in Bashkortostan/Russia included 1526 (81.1%) individuals undergoing ophthalmological and medical examinations with sonographic axial length measurement.

Prevalence Factors Associated With Vision Impairment and Blindness Among Individuals 85 Years and Older in Russia.

Importance: Visual performance is important for quality of life. However, vision impairment among adults 85 years and older has not been intensively examined.

Objective: To assess the prevalence of mild vision impairment (VI), moderate to severe vision impairment, and blindness and the factors associated with these conditions among a population 85 years and older.