Background: Vitiligo is a common depigmentation skin disease that affects the quality of life in many patients.
Aims: This study aims to investigate the effect of Medicago sativa methanol extract on the treatment of skin hypopigmentation disorders.
Methods: Antioxidant activity and phytochemical constituents of the extract were determined using DDPH assay, Folin-Ciocalteu, AlCl and HPLC-MS/MS analysis.