A Two-Stage Optimization Approach for Healthcare Facility Location- Allocation Problems With Service Delivering Based on Genetic Algorithm.

This study assesses a multi-period capacitated maximal-covering location-allocation model for healthcare services, taking interservice referral as well as equity access into account. A two-stage optimization strategy is used to formulate the model. In the first stage, facilities are located to maximize covered demand, and in the second stage, patients are allocated to capacitated facilities based on their radius of coverage over multiple time periods.

Extraction of pumpkin peel extract using supercritical CO and subcritical water technology: Enhancing oxidative stability of canola oil.

In this study, subcritical water extraction (SWE) and the supercritical fluid extraction (SFE) methods were used for the extraction of pumpkin peel extract. Total phenolic content and carotenoid compounds of extracts were measured. The extracts were added to canola oil at a concentration of 400 ppm and were stored at 30 °C for 60 days.