Publications by authors named "Azadeh Saber"

Background: Standard regression modeling may cause biased effect estimates in the presence of time-varying confounders affected by prior exposure. This study aimed to quantify the relationship between declining in modified creatinine index (MCI), as a surrogate marker of lean body mass, and mortality among end stage renal disease (ESRD) patients using G-estimation accounting appropriately for time-varying confounders.

Methods: A retrospective cohort of all registered ESRD patients (n = 553) was constructed over 8 years from 2011 to 2019, from 3 hemodialysis centers at Kerman, southeast of Iran.

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Objectives: An evaluation the effects of curcumin on inflammatory markers and lipid profiles among patients with chronic kidney diseases (CKD).

Methods: The electronic databases such as PubMed, and Scopus were searched systematically up until 12 December 2021. To evaluate the quality of the included studies, the Cochrane risk-of-bias tool for randomized trials was utilized.

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In this study, we aimed to estimate the causal effect of normalized protein catabolic rate (nPCR) on mortality among end-stage renal disease (ESRD) patients in the presence of time-varying confounding affected by prior exposure using g-estimation. Information about 553 ESRD patients was retrospectively collected over an 8-year period (2011-2019) from hemodialysis facilities in Kerman, Iran. nPCR was dichotomized as <1.

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Background: Several studies have been conducted on the relationship between a number of human leukocyte antigen (HLA) alleles and cytomegalovirus infection (CMV), in kidney transplant recipients, after transplantation. However, only a limited number of HLAs have been investigated, so far, and the results have been contradictory.

Objectives: This study aimed to investigate the relationship between 59 HLA alleles and the CMV infection, in transplant recipients, after kidney transplantation.

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Background: Some studies reported an association between low levels of vitamin D and the risk of infections, especially viral infections. Kidney transplant patients are at risk of opportunistic infections; however, no study has been conducted on the association between vitamin D levels and the risk of CMV infection.

Objectives: The aim of this study was to compare the level of vitamin D in two groups of patients with and without CMV infection within four months after the transplantation.

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Article Synopsis
  • Chemokines and their receptors are important in immunity and inflammation, and this study investigates their impact on kidney transplant rejection.
  • The study involved 100 donor-recipient pairs, evaluating two gene polymorphisms, CCR2-V64I and CCR5-Delta32, using genetic testing methods but found no significant relationships to acute rejection (AR) or delayed graft function (DGF).
  • Although no strong associations were found between the gene polymorphisms and transplant outcomes, factors like the cause of kidney failure and donor-recipient sex matching showed weak links to AR and DGF, highlighting the importance of considering these in transplant situations.
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