Fabrication of multifunctional mucoadhesive buccal patch for drug delivery applications.

Mucoadhesive buccal patch is a promising dosage form for a successful oral drug delivery, which provides unique advantages for various applications such as treatment of periodontal disease and postdental surgery disorders. The aim of this study is to synthesize a novel multifunctional mucoadhesive buccal patch in a multilayer reservoir design for therapeutic applications. The patches were fabricated through simultaneous electrospinning of chitosan/poly(vinylalcohol) (PVA)/ibuprofen and electrospraying of phenylalanine amino acid nanotubes (PhNTs) containing metronidazole into the electrospun mats through a layer-by-layer process.

Smart and Fragrant Garment via Surface Modification of Cotton Fabric With Cinnamon Oil/Stimuli Responsive PNIPAAm/Chitosan Nano Hydrogels.

This paper deals with obtaining aromatherapic textiles via applying stimuli-responsive poly N-isopropyl acryl amide (PNIPAAm) /chitosan (PNCS) nano hydrogels containing cinnamon oil on cotton fabric and looks into the treated fabric characteristics as an antibacterial and temperature/pH responsive fabric. The semi-batch surfactant-free dispersion polymerization method was proposed to the synthesis of PNCS nano particles. The incorporation of modified β -cyclodextrin ( β -CD) into the PNCS nanohydrogel was performed in order to prepare a hydrophobic(cinnamon oil) carrier embedded in stimuli-responsive nanohydrogel.

One-Pot Synthesis of Cu2 O/ZnO Nanoparticles at Present of Folic Acid to Improve UV-Protective Effect of Cotton Fabrics.

In this study, the effect of using folic acid on the in situ synthesis process of nanostructures has been investigated. Folic acid, as a biotemplate for synthesis of Cu2 O/ZnO, was used to improve the reducing and stabilizing the ability of cotton fabric and avoid agglomeration of the particles. Scanning electron microscopy images revealed that using folic acid caused the formation of particles with smaller sizes on the cotton fabric and X-ray diffraction confirmed the same crystalline pattern of nanoparticles in comparison with the previous synthesis process.