Sonic hedgehog signalling pathway: a complex network.

Sonic Hedgehog (Shh) signalling cascade is one of the intricate signal transduction mechanisms that govern the precisely regulated developmental processes of multicellular organisms. Along with establishing the patterns of cellular differentiation to direct complex organ formation, it also has an important role in post-embryonic tissue regeneration and repair processes. Especially, Shh signalling is implicated in the induction of multifarious neuronal populations in central nervous system.

A critique of the literature on etiology of eating disorders.

The development of eating disorders including anorexia nervosa, bulimia nervosa, binge eating disorder, and atypical eating disorders that affect many young women and even men in the productive period of their lives is complex and varied. While numbers of presumed risk factors contributing to the development of eating disorders are increasing, previous evidence for biological, psychological, developmental, and sociocultural effects on the development of eating disorders have not been conclusive. Despite the fact that a huge body of research has carefully examined the possible risk factors associated with the eating disorders, they have failed not only to uncover the exact etiology of eating disorders, but also to understand the interaction between different causes of eating disorders.

Spatially regulated adult neurogenesis.

Adult neurogenesis has been the center of attention for decades. Neuroscientists hope to understand the mechanism underlying this phenomenon that might provide a unique perception of brain repair in future. Neurogenesis is referred to the process in which neuronal stem cells and progenitors generate new neurons in non-pathologic setting.