Dynamic thiol/disulfide homeostasis in children with community-acquired pneumonia.

Background: Alteration in thiol level under oxidative stress may contribute to community-acquired pneumonia (CAP). The goal of this study was to determine whether there are changes in thiol/disulfide homeostasis and nitric oxide (NO) in children with CAP.

Methods: In total, 130 participants were involved in the study.

Contribution of the Rho-kinase to Systemic Sclerosis and Behçet's Disease.

Background: The small GTPase Rho family and its effectors, Rho-kinases (ROCK) play essential roles in the actin cytoskeleton organization and coordinate a broad range of cellular functions, such as inflammatory responses, cell contractility, migration, adhesion, proliferation, and apoptosis.

Methods: The goal of this work is to review existing literature about systemic sclerosis and Behçet's disease in relation to ROCK.

Results: There are some evidence that ROCK expression is elevated in patients with systemic sclerosis and Behçet's disease.