Publications by authors named "Ayyaru Jawahar"
Article Synopsis
- * Researchers isolated and sequenced genomes from 9 animal samples (4 cattle, 4 deer, and 1 buffalo) that died from tuberculosis and compared them to existing data, revealing a closed pangenome structure and a unique SNP in a virulence gene as a potential identification marker.
- * The findings indicate that this specific MTBC member is prevalent in South Asian animals, highlighting its zoonotic potential and the need for further evaluation of its impact on animal and human health.
Mycobacterium orygis has been isolated from several cases of tuberculosis in various species of animal in India but documentation of the histopathological lesions caused by this organism is scant. Lung and liver tissues with caseous nodules from cattle (n = 8), lung samples from spotted deer (Axis axis) (n = 5) and lung and mediastinal lymph node samples from buffalo (n = 9) were subjected to histopathology and isolation of Mycobacterium spp. Isolation was carried out using the BACTEC MGIT 960 Automated Mycobacterial Detection System and acid-fast positive cultures were identified to species level using polymerase chain reaction (PCR) employing published primer pairs.
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