Publications by authors named "Ayusa Nishimoto"
Article Synopsis
- In Euglena gracilis, ATP is generated through wax ester fermentation during anaerobic conditions, but this process is hindered by inhibition of mitochondrial complex I using rotenone and enhanced by the uncoupler CCCP.
- The study finds that the ADP/ATP ratio rises in anaerobic cells treated with either rotenone or CCCP, indicating a complex interplay in energy production.
- Gene silencing reveals key players in wax ester production, such as acyl-CoA dehydrogenase and electron transfer flavoprotein, suggesting that fatty acid synthesis occurs in mitochondria through reverse β-oxidation while anaerobic respiration utilizes trans-2-enoyl-CoA to produce ATP.
