Publications by authors named "Ayumi Ryu"
Article Synopsis
- Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is important for diagnosing pancreatic cancer and initiating targeted therapies, but sample insufficiency is a common issue that needs to be addressed.
- A study conducted at the Osaka International Cancer Institute involved 42 patients, comparing the effectiveness of oil blotting paper versus filter paper for fixing EUS-TA samples for analysis.
- Results showed that samples fixed with oil blotting paper had significantly larger tissue areas and a higher frequency of abundant tumor cells, suggesting it enhances sample adequacy for molecular testing.
Introduction: Cellprep® (CP) is a novel liquid-based cytology (LBC) system. This study aimed to assess the immunoreactivity of control samples stored long-term under two storage conditions using CP.
Methods: The immunoreactivity in control samples was evaluated under two sample storage conditions: CP vial storage at room temperature (RT: 20-25°C) and CP slide storage in a refrigerator (2-6°C).
Article Synopsis
- - The report emphasizes that multiple myeloma should be considered when diagnosing pancreatic tumors with associated bone lesions.
- - It suggests that examining both the pancreatic tumor and the bone lesions is crucial for accurate diagnosis.
- - By sampling from both areas, healthcare providers can improve their chances of identifying the correct condition.
Article Synopsis
- Cytology is a quick method for identifying liver tumors, and this study focused on its effectiveness in diagnosing malignancies through liver biopsies.
- The study involved comparing traditional cytology and on-site cytology with histopathology in patients with liver tumors, finding a high sensitivity (97.6%) for detecting malignancies.
- Results showed that non-HCC tumors had even higher detection rates than HCCs, and on-site cytology proved useful for making quick preliminary diagnoses, which is crucial for patients with advanced cancer who need rapid treatment.
Background: Although the incidence of cervical adenocarcinoma has consistently increased, especially among young women, there is no established best means for screening. This study evaluated the screening efficacy of CINtec PLUS (CINtec; p16/Ki67 double immunocytochemistry) expression in cervical glandular cells.
Methods: Cervical cytology was examined using abnormal glandular cells.
Introduction: Gastric-type mucinous carcinoma (GAS) of the uterine cervix is an adenocarcinoma subtype with a gastric phenotype that poses diagnostic pitfalls in cervical screening cytology because of its blunt morphologic atypia and the limited utility of human papillomavirus testing and ancillary immunochemical staining. Despite the recent widespread uptake of liquid-based cytology (LBC) systems, the cytomorphological features of GAS in LBC samples and the differential features between GAS and usual-type endocervical adenocarcinoma (UEA) remain unclear.
Methods: Eight GAS cases, all of which were surgically treated following histological confirmation, were examined.
Background: Pagetoid spread of urothelial carcinoma (UC) to the lower genital tract is quite a rare and diagnostically challenging condition. Pagetoid urothelial intraepithelial neoplasia extending to the vagina is difficult to diagnose, especially in remote recurrences without symptomatic or macroscopic lesions typical to Paget disease. However, its identification by cervical screening cytology is important because UC is often characterized by a long history of relapse.
View Article and Find Full Text PDFObjective: The aim of this study was to evaluate the reliability of estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) expression levels in Cellprep® (CP).
Study Design: We evaluated the stability of immunocytochemistry (ICC) of ER and HER2 for primary or recurrent breast cancer samples rinsed in CP vials. Samples were prepared from CP vials stored for 1-30 or 160-240 days.
Dacryocystocele is caused by nasolacrimal duct obstruction and results in cystic dilatation of the proximal part of the nasolacrimal duct, which is located inferomedial to the orbit, leading to fluid accumulation. It is important to consider that persistent congenital bilateral dacryocystoceles may cause neonatal nasal obstruction resulting in respiratory difficulty, and large dacryocystoceles may require surgical drainage. Ultrasonography demonstrates that congenital bilateral dacryocystoceles and normal eyeballs prenatally resemble two pairs of cystic "lesions" of different sizes.
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