Publications by authors named "Ayumi Otagaki"

Background & Aims: Nutritional assessment in allogeneic hematopoietic stem cell transplantation (allo-HSCT) is important and decreased skeletal muscle mass is a risk factor for the development of infection. Recently, it has become clear that qualitative rather than skeletal muscle mass loss is a marker that reflects post-transplant outcome, but its association with the development of infection remains unclear. Therefore, we assessed skeletal muscle status by body composition using bioelectrical impedance analysis (BIA) and investigated its association with the development of infection.

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Rationale: The radiographic density of the erector spinae muscle (ESM) is often decreased early after lung transplantation (LTx). The prognostic impact of this change has not been elucidated.

Objective: To investigate whether the decrease in the radiographic density of ESMs early after LTx is associated with a poor prognosis.

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Purpose: The 6-min walk test (6MWT) of allogenic hematopoietic stem cell transplantation (allo-HSCT) recipients has been gaining attention; however, minimal differences have not been reported. This study aimed to determine the minimal important difference (MID) in the 6MWT among hospitalized patients with allo-HSCT.

Materials And Methods: The MID of the 6MWT was calculated using three different methodologies based on an anchor-based method; basic anchor-based methods, linear regression analysis, and receiver operating characteristic (ROC) curve analysis.

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A decline in physical functions at the early stage of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a serious issue. Belt electrode-skeletal muscle electrical stimulation (B-SES) can induce significant muscle contractions with electrical stimulation and reduce muscle weakness. However, this approach has not been used in allo-HSCT patients.

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Article Synopsis
  • Multidisciplinary assessment of patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) is crucial, as skeletal muscle loss and quality serve as important prognostic indicators.
  • A study evaluated muscle quantity and quality in 186 adult patients using CT scans, highlighting that low radiographic density (RD) was linked to poor overall survival post-transplant.
  • The findings suggest incorporating muscle quality assessment into pretransplant screening and emphasize the need for rehabilitation programs aimed at enhancing both muscle quality and quantity to improve allo-HSCT outcomes.
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Objective: To retrospectively investigate the effect of early mobilization on the muscle strength and activities of daily living in patients with COVID-19 under mechanical ventilation.

Design: This was a single-center, retrospective, observational study.

Setting: Inpatient rehabilitation care in Japan.

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